Sex-related differences in pharmacokinetics and pharmacodynamics of frequently prescribed drugs: a review of the literature

A Farkouh, T Riedl, R Gottardi, M Czejka… - Advances in …, 2020 - Springer
… More recently, sex-specific approaches have been described eg for carboplatin dosing [32] …
relevant sex-related differences in terms of pharmacokinetics and pharmacodynamics as …

Race and sex associations with tacrolimus pharmacokinetics in stable kidney transplant recipients

KM Tornatore, CJ Meaney, K Attwood… - … : The Journal of …, 2022 - Wiley Online Library
… Categorical measures were summarized by race-sex groups using frequencies and relative
… There were no differences for glucose, prednisone or statin use, total cholesterol, low-…

Population pharmacodynamic modeling of intramuscular and oral dexamethasone and betamethasone effects on six biomarkers with circadian complexities in Indian …

W Krzyzanski, MA Milad, AH Jobe, T Peppard… - … and Pharmacodynamics, 2021 - Springer
steroids on cortisol, glucose, and cell trafficking responses in the studied women. The array
of relative … All subjects were of Indian ethnicity and were studied in India. The study inclusion …

Fifty Years of Unraveling the Clinical Pharmacology of Corticosteroids

KE Kyler, SJ Szefler - Journal of pharmaceutical sciences, 2023 - Elsevier
… , indicating that prednisone protein binding has little effect on prednisolone disposition. …
17 , while prednisolone pharmacokinetics differ only modestly in relation to sex and race (African-…

Pharmacokinetics and Pharmacodynamics of Repository Corticotropin Injection Compared With Synthetic ACTH1‐24 Depot and Methylprednisolone in Healthy …

N Poola, B Due, D Wright, LR Brooks… - … Pharmacology in Drug …, 2022 - Wiley Online Library
… exposure and for estimation of the prednisone dose equivalence of RCI and synthetic ACTH
1-… (83.3%) and were not of Hispanic or Latino ethnicity (83.3%). The mean age, body weight, …

Population pharmacodynamic modeling of intramuscular and oral dexamethasone and betamethasone effects on six biomarkers with circadian complexities in Indian …

K Wojciech, MA Milad, AH Jobe… - … Pharmacodynamics, 2021 - search.proquest.com
steroids on cortisol, glucose, and cell trafficking responses in the studied women. The array
of relative … All women in this study were of similar age, body weight, and the same ethnicity. …

Contributions of William Jusko to Development of Pharmacokinetic and Pharmacodynamic Models and Methods

DE Mager, RM Straubinger - Journal of Pharmaceutical Sciences, 2024 - Elsevier
relationship, and this behavior was obviated by relating drug … Sex and circadian prednisolone
effects on T-cell deactivation … Early studies to assess prednisone and prednisolone PK …

The role of sex, age and genetic polymorphisms of CYP enzymes on the pharmacokinetics of anticholinergic drugs

SC Trenaman, SK Bowles, MK Andrew… - Pharmacology …, 2021 - Wiley Online Library
Sex-related differences that may be influenced by anticholinergic drug exposure include …
To examine the effect of age, sex, and race on the pharmacokinetics, pharmacodynamics and …

Pharmacology considerations in women in lung disease and critical care

CC Eng, MS Heavner - Clinics in Chest Medicine, 2021 - chestmed.theclinics.com
… This article provides an overview of sex-related differences in drug pharmacokinetics and
pharmacodynamics (PKPD) in respiratory disease and critical illness. A focus on PKPD …

Clinical pharmacokinetics and pharmacodynamics of daratumumab

K Kim, MA Phelps - Clinical Pharmacokinetics, 2023 - Springer
… , DNA-alkylating agents, and corticosteroids. Following an … /hepatic function, age, sex, race,
weight, Eastern Cooperative … with immunoglobulin G myeloma compared with patients with …