Transplacental arsenic exposure produced 5-methylcytosine methylation changes and aberrant microRNA expressions in livers of male fetal mice
J Liu, S Gunewardena, JY Cui, CD Klaassen… - Toxicology, 2020 - Elsevier
… that arsenic exposure in utero may induce epigenetic … In summary, in utero arsenic exposure
induced global alterations … among 5000 comparable sites, arsenic exposure at the doses of …
induced global alterations … among 5000 comparable sites, arsenic exposure at the doses of …
Epigenetic modifications from arsenic exposure: A comprehensive review
A Chakraborty, S Ghosh, B Biswas, S Pramanik… - Science of the total …, 2022 - Elsevier
… and increased DNA methylation in CpG sites of Line-1 and to a … with total prenatal urinary
arsenic concentration during early … prenatal arsenic exposure in a sex-dependent approach. …
arsenic concentration during early … prenatal arsenic exposure in a sex-dependent approach. …
DNA methylation changes induced by prenatal toxic metal exposure: An overview of epidemiological evidence
A Vaiserman, O Lushchak - Environmental Epigenetics, 2021 - academic.oup.com
… epigenetic modifications in affected offspring. In Bangladesh, … Specifically, altered
methylation of 12 CpG sites mediated … in utero has been related to lower global 5-methylcytosine …
methylation of 12 CpG sites mediated … in utero has been related to lower global 5-methylcytosine …
Locus-specific differential DNA methylation and urinary arsenic: an epigenome-wide association study in blood among adults with low-to-moderate arsenic exposure
AK Bozack, A Domingo-Relloso, K Haack… - Environmental …, 2020 - ehp.niehs.nih.gov
… sites; however, the identity and number of CpGs identified (… the association between
prenatal As exposure and DNA … were identified, it is not known if alterations in these epigenetic …
prenatal As exposure and DNA … were identified, it is not known if alterations in these epigenetic …
Prenatal metal exposure, cord blood DNA methylation and persistence in childhood: an epigenome-wide association study of 12 metals
… associated with alterations in … determine the generalizability of our findings. Further research
may also provide insights to the effect of mixtures of prenatal metal exposures on epigenetic …
may also provide insights to the effect of mixtures of prenatal metal exposures on epigenetic …
Environmental epigenetics and genome flexibility: Focus on 5-hydroxymethylcytosine
OA Efimova, AS Koltsova, MI Krapivin… - International Journal of …, 2020 - mdpi.com
… , 5-methylcytosine (5mC) [3], which is a major player in … -induced epigenetic alterations that
are responsible for modifications … Perinatal BPA exposure increases Kcnq1 expression in the …
are responsible for modifications … Perinatal BPA exposure increases Kcnq1 expression in the …
Arsenic exposure and human blood DNA methylation and hydroxymethylation profiles in two diverse populations from Bangladesh and Spain
… in As-related epigenetic sites across the study populations may … The main finding is that
numerous DHPs and DMPs in our … As-induced organ-specific alterations were found for 5-hmC, …
numerous DHPs and DMPs in our … As-induced organ-specific alterations were found for 5-hmC, …
Prenatal lead (Pb) exposure and peripheral blood DNA methylation (5mC) and hydroxymethylation (5hmC) in Mexican adolescents from the ELEMENT birth cohort
CA Rygiel, JM Goodrich… - Environmental …, 2021 - ehp.niehs.nih.gov
… Epigenetic modifications are mitotically heritable molecular changes that regulate gene
expression without altering the underlying DNA sequence. DNA 5-methylcytosine (… CpG sites as …
expression without altering the underlying DNA sequence. DNA 5-methylcytosine (… CpG sites as …
Developmental arsenic exposure impairs cognition, directly targets DNMT3A, and reduces DNA methylation
… specific for 5′-methylcytosine (5meC; Fig EV1C). Upon … As shown in Fig 1D, the average
CpG site methylation on all … The mRNA level of DNMT3A was not significantly altered upon …
CpG site methylation on all … The mRNA level of DNMT3A was not significantly altered upon …
Tissue and sex-specific programming of DNA methylation by perinatal lead exposure: implications for environmental epigenetics studies
… 5th-position of cytosines (5-methylcytosine, 5mC) occurring in … perinatal Pb exposure
would lead to sex-specific alterations … that Pb-altered methylation of CpG sites in key organ …
would lead to sex-specific alterations … that Pb-altered methylation of CpG sites in key organ …