[HTML][HTML] Intrauterine growth restriction: Clinical consequences on health and disease at adulthood

JB Armengaud, C Yzydorczyk, B Siddeek… - Reproductive …, 2021 - Elsevier
… This phenomenon is known as ‘fetal programming’… fetal insulin secretion or insulin sensitivity
of fetal organs [95]. It is an illustration of the so-called thrifty phenotype: a hostile intrauterine

[HTML][HTML] Maternal food restriction-induced intrauterine growth restriction in a rat model leads to sex-specific adipogenic programming

S Sreekantha, Y Wang, R Sakurai, J Liu… - FASEB journal: official …, 2020 - ncbi.nlm.nih.gov
fetal programming”, and the consequent “fetal origins of adult diseases” has been well described
in offspring following intrauterine growth restriction … cfd (regulates insulin secretion) and …

[HTML][HTML] Highlighting the trajectory from intrauterine growth restriction to future obesity

KV Gantenbein, C Kanaka-Gantenbein - Frontiers in endocrinology, 2022 - frontiersin.org
Fetal growth is regulated by hormones mainly secreted by the … of fetal growth is fetal insulin,
while insulin secreted by the beta-… fetal circulation drives the production of insulin by the fetal

Long-term metabolic consequences of intrauterine growth restriction

KE Joung, J Lee, JH Kim - Current Pediatrics Reports, 2020 - Springer
… related to developmental programming in fetal period and … of β-cell proliferation and insulin
secretion and were reported … In guinea pigs, fetal growth restriction resulted in alteration of …

Insights into the mechanisms of fetal growth restriction-induced programming of hypertension

B Bhunu, I Riccio, S Intapad - Integrated Blood Pressure Control, 2021 - Taylor & Francis
… animal studies have shown that fetal growth restriction (FGR), … in the field of fetal programming
of hypertension and a brief … Insulin and leptin are the two principal hormones regulating …

Intrauterine growth restriction: the controversial role of perinatal adipocytokines in the prediction of metabolic adult disease

DD Briana, A Malamitsi-Puchner - The Journal of Maternal-Fetal & …, 2021 - Taylor & Francis
… “prenatal/fetal programming,” take place and predispose to chronic diseases [Citation4]. …
lipid metabolism in insulin-sensitive tissues. It enhances intrauterine growth through its insulin-…

[HTML][HTML] The role of cellular stress in intrauterine growth restriction and postnatal dysmetabolism

SL Oke, DB Hardy - International Journal of Molecular Sciences, 2021 - mdpi.com
insulin growth factor 1 (IGF-1) in the liver and blood [28]. Based on Barker’s ‘thrifty phenotype’
hypothesis, which states that fetal programming … and impaired insulin secretion at birth [52]…

Nutritional and developmental programming effects of insulin

L Dearden, SG Bouret… - Journal of …, 2021 - Wiley Online Library
… receptor or signalling components downstream results in severe growth retardation. …
the important impact of maternal environment on fetal insulin release and therefore growth. …

Fetal growth and intrauterine epigenetic programming of obesity and cardiometabolic disease

D Harary, A Akinyemi, MJ Charron, M Fuloria - Neoreviews, 2022 - publications.aap.org
intrauterine growth restriction (IUGR), an extreme phenotype of LBW in which the fetus fails
to meet its growth … and/or insulin resistance are associated with an increase in child adiposity. …

[HTML][HTML] Role of prenatal nutrition in the development of insulin resistance in children

A Blasetti, A Quarta, M Guarino, I Cicolini, D Iannucci… - Nutrients, 2022 - mdpi.com
pregnancy seems to damage fetal metabolism programming; … Intrauterine growth restriction
(IUGR) induced by unbalanced … and delayed rise in insulin secretion after meals, leading to …