Pirfenidone and vitamin D mitigate renal fibrosis induced by doxorubicin in mice with Ehrlich solid tumor

RM Hazem, SA Antar, YK Nafea, AA Al-Karmalawy… - Life Sciences, 2022 - Elsevier
tumor weight and volume by vitamin D was supported by Preclinical evidence suggesting
that biologically active vitamin D … synthesis, which helped to prevent kidney fibrosis [75,76]. It …

[HTML][HTML] Vitamin D supplementation and prevention of cardiovascular disease and cancer in the Finnish Vitamin D Trial: a randomized controlled trial

JK Virtanen, T Nurmi, A Aro… - The American journal of …, 2022 - Elsevier
… 25(OH)D is metabolized to the physiologically active form 1,… vitamin D supplementation and
in most trials the vitamin D dose was too low to induce significant changes in serum 25(OH)D

Effect of vitamin D3 supplements on development of advanced cancer: a secondary analysis of the VITAL randomized clinical trial

PD Chandler, WY Chen, ON Ajala, A Hazra… - JAMA network …, 2020 - jamanetwork.com
… acids (1 g/d) for primary prevention of cancer and cardiovascular … to receive vitamin D 3 ,
marine omega-3 fatty acids, both active … the mean BMI for active vitamin D vs placebo within the …

The role of classical and novel forms of vitamin D in the pathogenesis and progression of nonmelanoma skin cancers

AT Slominski, AA Brożyna, MA Zmijewski… - Sunlight, Vitamin D and …, 2020 - Springer
Vitamin D3 is a prohormone that is activated by sequential … function in order to prevent rejection
of their transplanted organ… cancers, particularly cutaneous squamous cell carcinomas [6]. …

Vitamin D signaling in inflammation and cancer: Molecular mechanisms and therapeutic implications

A El-Sharkawy, A Malki - Molecules, 2020 - mdpi.com
… of vitamin D analogues or the active metabolite of vitamin D … potential of vitamin D and its
analogs in the prevention and … squamous cell carcinoma [185], as well as in several human …

Regular use of vitamin D supplement is associated with fewer melanoma cases compared to non-use: a cross-sectional study in 498 adult subjects at risk of skin …

E Kanasuo, H Siiskonen, S Haimakainen… - Melanoma …, 2023 - journals.lww.com
… , nevi, basal, and squamous cell carcinoma. In contrast, there … the coin is that public sun
protection campaigns have led to … that generate biologically active vitamin D metabolites (…

Calcifediol (25OH Vitamin D3) Deficiency: A Risk Factor from Early to Old Age

R Bouillon, L Antonio, OR Olarte - Nutrients, 2022 - mdpi.com
… of vitamin D or of vitamin D action causes rickets. We also know that approximately 10 ug of
vitamin D per day can prevent … that local regulation of active vitamin D may be important for …

Current updates and future perspectives on the management of renal cell carcinoma

D Singh - Life sciences, 2021 - Elsevier
… 4) for the protection of renal cancer instigating cells and … The expression of vitamin D
receptors in RCC is reduced or … of renal cancer cells through hormone-activated pathways. …

Vitamin D-induced molecular mechanisms to potentiate cancer therapy and to reverse drug-resistance in cancer cells

M Negri, A Gentile, C de Angelis, T Montò, R Patalano… - Nutrients, 2020 - mdpi.com
… hydroxylations to be converted to fully active vitamin D. The first hydroxylation mainly occurs
… , to obtain 25(OH)D, the major circulating, but less active, form of vitamin D [2]. Although …

Vitamin D, marine n-3 fatty acids, and primary prevention of cardiovascular disease current evidence

JAE Manson, SS Bassuk, NR Cook, IM Lee… - Circulation …, 2020 - Am Heart Assoc
active n-3 FA and placebo groups (55% increase) and in 25(OH)D levels between the active
vitamin D … n-3 index with active n-3 FA was ≈4.1% and the achieved serum 25(OH)D with …