Natural products for the prevention and treatment of cholestasis: A review

X Ma, Y Jiang, W Zhang, J Wang, R Wang… - Phytotherapy …, 2020 - Wiley Online Library
… characteristics of increased in vivo exposure and delayed in vivo … In addition, the ethanol
extract of Caesalpinia pyramidalis … against lithocholic acid (LCA)-induced hepatotoxicity and …

[HTML][HTML] Scoparone attenuates cholestatic liver injury through regulating hepatic bile acid metabolism, ameliorating periductal fibrosis and inhibiting inflammatory …

J Hao, X Shen, K Lu, Y Xu, Y Chen, J Liu… - Pharmacological …, 2023 - Elsevier
… of the herbal medicine Artemisia capillaris Thunb that is used … of model establishment by
inhalation of carbon dioxide. … noxious endogenous bile acid of lithocholic acid (LCA) after DDC …

Anti-malarial drug: the emerging role of artemisinin and its derivatives in liver disease treatment

Y Xiong, J Huang - Chinese Medicine, 2021 - Springer
exposure to lithocholic acid (LCA) caused liver injury, but the anti-inflammatory activity of
artemisinin extract … malaria suffered from severe acute cholestatic hepatitis, combined with …

The potential application of chinese medicine in liver diseases: a new opportunity

K Fu, C Wang, C Ma, H Zhou, Y Li - Frontiers in Pharmacology, 2021 - frontiersin.org
… is an important factor for the prevention and treatment of liver … and developing artemisinin
in Artemisia annua Linn. It is a … Cholestasis means that the bile cannot flow from the liver to …

The effect of lithocholic acid on the gut-liver axis

W Sheng, G Ji, L Zhang - Frontiers in Pharmacology, 2022 - frontiersin.org
… of LCA detoxification and reduce LCA-induced liver damage. For example, glycyrrhizin…
extract and artemisinin treatment prevent hepatotoxicity and cholestasis caused by LCA exposure

Scoparone as a therapeutic drug in liver diseases: Pharmacology, pharmacokinetics and molecular mechanisms of action

Y Hui, X Wang, Z Yu, X Fan, B Cui, T Zhao… - Pharmacological …, 2020 - Elsevier
… of hepatic dysfunction, cholestasis and jaundice for over … Artemisinin, For instance, is an
extract that is prepared from … CAR accelerates liver injury in lithocholic acid-treated or bile …

[HTML][HTML] Hyperoside attenuates non-alcoholic fatty liver disease in rats via cholesterol metabolism and bile acid metabolism

S Wang, F Sheng, L Zou, J Xiao, P Li - Journal of advanced research, 2021 - Elsevier
… role for hyperoside in the prevention and treatment of NAFLD … In our study, the phosphorylation
of ACC was induced by the … , for example, increased exposure to hydrophobic BAs leads …

Cooperative interaction of phenolic acids and flavonoids contained in activated charcoal with herb extracts, involving cholesterol, bile acid, and Fxr/Pxr activation in …

Y Zhang, Z Lin, L Wang, X Guo, Z Hao, Z Li… - Antioxidants, 2022 - mdpi.com
… , Portulaca oleracea L., Artemisia argyi Folium, and Pteris … determined at different times
after exposure to T-2 mycotoxin. … Increased bile acids, mainly consisting of lithocholic acid (…

The Effect of the Artemisinin on the Liver Functions in Iraqi Patients Infected by Ovarian Cancer

NFY Al-Saarag, FG Talab… - Annals of the Romanian …, 2021 - annalsofrscb.ro
Preventive effect of artemisinin extract against cholestasis induced via lithocholic acid
exposure… The effects of Artemisia aucheri extract on hepatotoxicity induced by thioacetamide in …

Natural products targeting liver X receptors or farnesoid X receptor

J She, T Gu, X Pang, Y Liu, L Tang… - Frontiers in …, 2022 - frontiersin.org
… found in the aerial part of Artemisia dracunculus L., which is … 75 mg/kg dose of ANIT-induced
cholestasis and liver injury as … for the prevention and therapy of cholestatic liver disease (…