[HTML][HTML] Aberrant peribiliary gland niche exacerbates fibrosis in primary sclerosing cholangitis and a potential therapeutic strategy

S Wu, Y Cao, H Lu, X Qi, J Sun, Y Ye, L Gong - Biomedicine & …, 2022 - Elsevier
… we established acute and chronic mouse models of PSC through … C57BL/6 J mice were orally
administered ANIT for 2 days … like) and alternatively activated (M2-like) MoMFs in mice with …

[HTML][HTML] Aryl hydrocarbon receptor deficiency in intestinal epithelial cells aggravates alcohol-related liver disease

M Qian, J Liu, D Zhao, P Cai, C Pan, W Jia… - Cellular and molecular …, 2022 - Elsevier
… expression in mice and human beings. Compared with Ahr fl/… hepaticus–treated mouse
hepatocyte alpha mouse liver 12 (… Administration of IBA in C57BL/6 mice showed obvious liver

[HTML][HTML] Chronic ingestion of Primex-Z, compared with other common fat sources, drives worse liver injury and enhanced susceptibility to bacterial infections

MM Antunes, AB Diniz, HM Castro-Oliveira… - Nutrition, 2021 - Elsevier
Male C57BL/6 mice were fed a control diet, and four different … Here we developed four
variations of mouse chow with high-… However, we observed a significant increase in body

[HTML][HTML] Synthetic human ABCB4 mRNA therapy rescues severe liver disease phenotype in a BALB/c. Abcb4-/-mouse model of PFIC3

G Wei, J Cao, P Huang, P An, D Badlani, KA Vaid… - Journal of …, 2021 - Elsevier
… , including liver weight, body weight, liver enzymes, and … , we used codon optimisation similar
to previously described … more fibrotic than either FVB 20 or C57BL/6 strain 39 ). Moreover, …

Aronia melanocarpa Prevents Alcohol‐Induced Chronic Liver Injury via Regulation of Nrf2 Signaling in C57BL/6 Mice

Z Wang, Y Liu, X Zhao, S Liu, Y Liu… - Oxidative Medicine and …, 2020 - Wiley Online Library
… with significant risks such as infection, especially in this … a C57BL/6 mouse model of
alcohol-induced chronic liver … , primary biliary cirrhosis, and chronic hepatitis in humans [49, …

Conventional type 1 dendritic cells are essential for the development of primary biliary cholangitis

D Reuveni, S Assi, Y Gore, E Brazowski… - Liver …, 2024 - Wiley Online Library
C57Bl/6 mice were exposed to 950 rad total body radiation. … CD8 T- cell immunity to infection
of the skin with herpes simplex … the development of murine primary biliary cholangitis. Front …

IgY antibodies against cytolysin reduce ethanol-induced liver disease in mice

N Cabré, P Hartmann, C Llorente, T Kouno, Y Wang… - Hepatology, 2023 - journals.lww.com
… -humanized mouse model of ethanol-induced liver disease. … We did not find differences in
serum LPS when C57BL/6 … gastrointestinal infections, 25 treatment of fungal infections, 26 …

[HTML][HTML] Mouse models of hepatocellular carcinoma: classification, advancement, and application

S Liu, F Huang, G Ru, Y Wang, B Zhang, X Chen… - Frontiers in …, 2022 - frontiersin.org
… of liver cells 4 weeks after birth and induce primary liver tumors … transgenic mouse model of
chronic carriers of HBV infection (… Normal mice (BALB/C, C57BL/6, etc.) or rebuilding human-…

HBV genotype: a significant risk factor in determining which patients with chronic HBV infection should undergo surveillance for HCC: the hepatitis B Alaska study

BJ McMahon, LD Nolen, M Snowball, C Homan… - Hepatology, 2021 - journals.lww.com
Primary hepatocytes from C57BL/6 mice 6‐8 weeks old were … ( 20 ) In brief, mouse livers
were perfused 2 times with liver … , we focused on the ER‐related candidates by determining the …

Kupffer cell–like Syncytia replenish resident macrophage function in the Fibrotic liver

M Peiseler, B Araujo David, J Zindel, BGJ Surewaard… - Science, 2023 - science.org
… and reduced susceptibility to infection. CRIg-expresssing … We used a mouse model of liver
fibrosis and human tissue to … population of tissue macrophages in the human body (3). KCs …