… most prevalent form of primary glomerulonephritis, has growing … staining may colocalize with
C3 deposits and correlate with … may be affected by genetic predisposition, which influences …

… The primary objective of the current study was to identify … Focal granular IgM deposits were
found along segments of the … with pathogenic variants in complement genes (ie, C3, n=3, and …

… The most common site of infection was skin in peri- (23 of 97, … blockers were significant risk
factors for progression to kidney … Patients with isolated C3 deposits as compared with patients …

… including atypical hemolytic uremic syndrome (aHUS), C3 … microscopy examination suggests
dense deposit disease (DDD). … labeled primary aHUS. Recent work has highlighted that …

… common primary glomerular diseases such as IgA nephropathy, membranous glomerulonephritis
(MGN), and diabetic kidney disease (… C3 deposits, and the 2 common entities that are …

… C3 deposits (fH −/− mice) and in mice with scant glomerular … 51, 52, 53, 54 Even if the FHRs
are not the primary drivers of … and are consultants for Q32 Bio, Inc., a company developing …

… with primary podocytopathy had APOL1 high risk genotypes. … , C3, kappa and lambda light
chain. EM displayed mesangial, para-mesangial and rare subendothelial electron deposits. …

… ) nephritis primarily show MBL, MASP, and C4d deposits signifying … Among the primary
deficiencies of the components of the C1 … SLE is very rare in isolated C3 deficiency. Patients with …

… these entities pathophysiologically [10]. In aHUS, … Later, primary goat anti-factor H antibody
was added into the … mutation in the C3 gene and a heterozygous risk haplotype in MCP…

… IgAN is the most common primary glomerular disease, … Properdin is co-deposited with IgA
and C3 in 75%–100% of … activation, like in atypical haemolytic uremic syndrome (aHUS), but …