Approach to kidney biopsy: core curriculum 2022
… of inflammatory cells and fibrous organization. Crescents are … strong C3 deposits by IF, and
hump-shaped subepithelial deposits … hyperoxaluria) or primary due to genetic defects in key …
hump-shaped subepithelial deposits … hyperoxaluria) or primary due to genetic defects in key …
C3‐dependent effector functions of complement
A Zarantonello, M Revel, A Grunenwald… - Immunological …, 2023 - Wiley Online Library
… molecular mechanism and structural organization of the C5 … produce C3 (and hence stain
positive) and deposit C3 activation … Due to its primary role in IC clearance, CR1 is an important …
positive) and deposit C3 activation … Due to its primary role in IC clearance, CR1 is an important …
Chronic thrombotic microangiopathy in patients with a C3 gain of function protein
SA Timmermans, MH Abdul-Hamid… - Nephrology Dialysis …, 2020 - academic.oup.com
… in primary atypical haemolytic uraemic syndrome (aHUS) [2]. … C3c but not immune complex
deposits were found along … by the European Medicines Agency. Both other recipients (…
deposits were found along … by the European Medicines Agency. Both other recipients (…
Histopathology of Urinary System
Z Uddin, A Memon, M Arif - Atlas of Diagnostic and Predictive …, 2020 - Springer
… microscopic features of ‘primary glomerulopathies’ and utility … type II MCGN shows C3-dominant
deposits in mesangium and … Haemolytic-uremic syndrome: Haemolytic-uremic syndrome …
deposits in mesangium and … Haemolytic-uremic syndrome: Haemolytic-uremic syndrome …
Thrombotic microangiopathy due to primary antiphospholipid syndrome: successful treatment with eculizumab
C Pala, E Parenti, G Vizzini, D Gianfreda… - Journal of …, 2023 - Springer
… described as a distinct histopathological entity in 1999, the so-… anti-dsDNA) and had C3
and C4 hypocomplementemia. At … There is no evidence of electron-dense deposits, ruling out …
and C4 hypocomplementemia. At … There is no evidence of electron-dense deposits, ruling out …
Primary Immunodeficiencies of Complement
PD Arkwright - Primary and Secondary Immunodeficiency: A Case …, 2021 - Springer
… of the C3 activity (C3 gain of function, Factor H, Factor I, … disease (aHUS or
membranoproliferative glomerulonephritis… , membranoproliferative/dense deposit glomerulopathy, …
membranoproliferative glomerulonephritis… , membranoproliferative/dense deposit glomerulopathy, …
Autoantibodies and Kidney Diseases
R Topaloglu, TK Levart, M Nagata, T Avcin - Pediatric Nephrology, 2022 - Springer
… APS had lupus nephritis and 5% of patients with primary APS had renal … finding of bright
linear IgG deposits along GBM is seen by … Atypical haemolytic uremic syndrome complicated by …
linear IgG deposits along GBM is seen by … Atypical haemolytic uremic syndrome complicated by …
Kidney disease in antiphospholipid antibody syndrome: Risk factors, pathophysiology and management
M Scheen, A Adedjouma, E Esteve, D Buob… - Autoimmunity …, 2022 - Elsevier
… “Seronegative APLS’ is becoming recognized as a distinct entity that encompasses the …
and immune deposits on immunofluorescence are typically absent in primary APLSN [21,25]…
and immune deposits on immunofluorescence are typically absent in primary APLSN [21,25]…
Urinalysis and Diagnostic Tests
RSBA Goldfarb-Rumyantzev… - Clinical Handbook of …, 2023 - books.google.com
… Uses: Provides enhanced contrast of object edges and of … is the most common form of
primary glomerulonephritis, with as … complex MPGN if Ig and/or C3 deposits are found on IF, …
primary glomerulonephritis, with as … complex MPGN if Ig and/or C3 deposits are found on IF, …
Selective binding of heparin/heparan sulfate oligosaccharides to factor H and factor H-related proteins: therapeutic potential for C3 glomerulopathies
MA Loeven, ML Maciej-Hulme, C Yanginlar… - Frontiers in …, 2021 - frontiersin.org
… C3G was diagnosed by the presence of C3 deposits by … FHRs proteins with purified HS
isolated from glycocalyx (HS Glx ) … Most likely, our primary finding that 2-O-desulfated heparin can …
isolated from glycocalyx (HS Glx ) … Most likely, our primary finding that 2-O-desulfated heparin can …