Extraction and Purification of Podophyllotoxin from Eastern Red Cedar (Juniperus virginiana L.) in Oklahoma

KR Stenmark - 2021 - search.proquest.com
Podophyllotoxin (ptox) is a pharmaceutical derived from plants used in a broad spectrum of
medicinal treatments ranging from inflammatory diseases to cancer. Originally sourced from …

[HTML][HTML] Podophyllotoxin-polyacrylic acid conjugate micelles: improved anticancer efficacy against multidrug-resistant breast cancer

PS Kumbhar, AM Sakate, OB Patil… - Journal of the Egyptian …, 2020 - Springer
Podophyllotoxin (PPT) is a naturally occurring compound obtained from the roots of Podophyllum
species… The zeta potential of PPC micelles was found to be −37.3 mV. Furthermore, the …

[HTML][HTML] Dormancy release of seeds of Podophyllum hexandrum Royle accompanied by changes in phytochemicals and inorganic elements

X Jiu, H Chen, T Du, XW Jia, D Liu, JJ Meng, XJ Xu - Plos one, 2023 - journals.plos.org
Podophyllotoxin, a lignan component in P. … outer top, that is, an increase in the growth
potential of the seed embryo. P. … ABA is produced in the endosperm and transported to the seed …

Synthesis and biological evaluation of cytotoxic activity of novel podophyllotoxin derivatives incorporating piperazinyl-cinnamic amide moieties

X Zhang, T Yang, X Jin, K Lin, X Dai, T Gao… - Bioorganic …, 2022 - Elsevier
… plant species of Podophyllum family, … potential of mitochondrial membrane potential, JC-1
cannot gather in the matrix of the mitochondria. At this time, JC-1 is a monomer and produce

[HTML][HTML] Fungal endophytes as efficient sources of plant-derived bioactive compounds and their prospective applications in natural product drug discovery: Insights …

A Singh, DK Singh, RN Kharwar, JF White, SK Gond - Microorganisms, 2021 - mdpi.com
… numbers of natural products are either produced by microbes or a … hexandrum that efficiently
produces podophyllotoxin and … from the roots of Podophyllum emodi, and Fusarium sp. from …

[HTML][HTML] The Endophytes: A New Resource for Vulnerable Plant Bioactive Compounds

M Fazeli - Medicinal Plants-Chemical, Biochemical, and …, 2024 - intechopen.com
… The production of effective plant … produce bioactive such as its host. Microorganisms are
an attractive source of new biomaterials; also, they have the potential to increase the production

Recent advances toward development of plant cell culture process for sustainable production of lignans and their health benefits

AMM Gabr, HB Mabrok, O Sytar… - … cells for the production of …, 2021 - Springer
… Today, the potential of plant cells to produce secondary … It is currently produced largely
from Podophyllum hexandrum … of Podophyllum peltatum to produce podophyllotoxin were …

Recent advances in natural product-based anticancer agents

AS Negi, S Jain - Studies in Natural Products Chemistry, 2022 - Elsevier
… origin having potential anticancer activities. … produce a diverse class of compounds, which
may modulate various biological targets [3], [4]. Podophyllotoxin from Podophyllum hexandrum

[HTML][HTML] Plant endophytes and epiphytes: Burgeoning sources of known and “unknown” cytotoxic and antibiotic agents?

DJ Newman, GM Cragg - Planta medica, 2020 - thieme-connect.com
… Another potential reason is inhibition of the producing … fungi that upon fermentation produced
podophyllotoxin. Puri et al. … the rhizome of a Podophyllum hexandrum species, produced

[HTML][HTML] Green Ultrasound-Assisted Extraction of Podophyllotoxin from Juniperus scopulorum Needles

C Verret, A Rakotondramavo, S Renouard - Applied Sciences, 2023 - mdpi.com
… of Podophyllum peltatum or Sinopodophyllum hexandrum … is therefore a potentially creditable
source of podophyllotoxin. … that could stimulate podophyllotoxin production, along the lines …