Identification of tumor-associated antigens with diagnostic ability of colorectal cancer by in-depth immunomic and seroproteomic analysis

M Garranzo-Asensio, P San Segundo-Acosta… - Journal of …, 2020 - Elsevier
… a humoral immune response in CRC patients. The seroproteomic approach relied on the
immunoprecipitation with patient-… The gradient profile was set as follows: 0%–35% solvent B for …

IgM and IgA augmented autoantibody signatures improve early‐stage detection of colorectal cancer prior to nodal and distant spread

MSI Roney, C Lanagan, YH Sheng… - Clinical & …, 2021 - Wiley Online Library
… The array was used to profile IgG, IgM and IgA antibody … aid in cancer diagnosis, particularly
in the early stages of cancer … IgA immune responses specific to selected tumor antigens are …

The profile and prognostic value of circulating lymphocyte subsets in metastatic colon cancer

J Xu, R Zhang, Q Peng, Z Jia, S Xiao, N Sun… - International …, 2023 - Elsevier
… and metastasis at the time of diagnosis, and the 5-year … immune system of colon cancer
patients [8], as well as other … (carcinoembryonic antigen), CA19-9 (Carbohydrate antigen 19–9), …

[HTML][HTML] Identification of the antigens recognised by colorectal cancer patients using sera from patients who exhibit a Crohn's-like lymphoid reaction

VB Boncheva, M Linnebacher, S Kdimati, H Draper… - Biomolecules, 2022 - mdpi.com
… expression profiles in CRC patients (p = 8.25 × 10 −145 ). … in human cancers and regulates
PAK4 in colon cancer. Acts … immune response into the tumour as part of the CLR reaction, we …

[HTML][HTML] Autoantibodies in the diagnosis, prognosis, and prediction of colorectal cancer

R Niloofa, MI De Zoysa… - Journal of Cancer …, 2021 - journals.lww.com
… [ 17 19 27 ] The autoantibody profile against the cell … combinations of colorectal cancer
tumor-associated antigens … This, in turn, stimulates the humoral immune response to produce …

[HTML][HTML] Autoimmunity profiles as prognostic indicators in patients with colorectal cancer versus those with cancer at other sites: a prospective study

P Sena, S Mancini, J Bertacchini, G Carnevale… - Cancers, 2021 - mdpi.com
… associated antigens, TAA), or by antigens generally hidden … such as colonoscopies for large
bowel cancer. In this context, … of increased humoral immune response in cancer patients, the …

[HTML][HTML] Immune cell infiltration-associated signature in colon cancer and its prognostic implications

D Deng, X Luo, S Zhang, Z Xu - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
… that the patients with the gene cluster A profile had better … antigens and activate the naive
T cells [36], and the increase of plasma cells indicates an obvious humoral immune response

The diagnostic, prognostic, and therapeutic potential of adaptive immune receptor repertoire profiling in cancer

LG Cowell - Cancer research, 2020 - AACR
… Lymphocyte antigen receptor repertoire deep sequencing data … complex interactions between
cancer, the immune system, and … Colorectal cancer Cancer peptide vaccine + oxaliplatin …

[HTML][HTML] Humoral immunoprofiling identifies novel biomarkers and an immune suppressive autoantibody phenotype at the site of disease in pancreatic ductal …

PWM Maimela, M Smith, AJM Nel, SDP Bernam… - … in Oncology, 2024 - frontiersin.org
… the immune response against these antigens should aid in … them attractive candidates
for cancer diagnosis, monitoring, and … profiling against 262 cancer-testis and tumor-associated …

[HTML][HTML] Comparative proteome identifies complement component 3-mediated immune response as key difference of colon adenocarcinoma and rectal …

JZ Liang, XL Liang, LY Zhong, CT Wu, J Zhang… - … in oncology, 2021 - frontiersin.org
… study, we profiled the protein difference between 20 cases of … biomarkers between colon
cancer and rectal cancer, we … antigen, humoral immune response, neutrophil mediated …