Sex differences in the effects of mild traumatic brain injury and progesterone treatment on anxiety-like behavior and fear conditioning in rats

LC Fox, JL Scholl, GM Palmer, GL Forster… - Experimental …, 2023 - Elsevier
Progesterone at the same dose also reduces cerebral edema after moderate-to-severe TBI
… (C) A weak correlation is present between time spent in open arms and distance traveled in …

[HTML][HTML] … outcomes, and neuroprotective effect after progesterone administration in ovariectomized rats with traumatic brain injury: Role of RU486 progesterone …

L Amirkhosravi, M Khaksari, V Sheibani… - Iranian Journal of …, 2021 - ncbi.nlm.nih.gov
reduces the neuroprotective effects of progesterone against oxygen-glucose deprivation/re-oxygenation-induced
In agreement with the useful role of P4 in improving anxiety after TBI in …

Progesterone treatment following traumatic brain injury in the 11-day-old rat attenuates cognitive deficits and neuronal hyperexcitability in adolescence

D Lengel, JW Huh, JR Barson, R Raghupathi - Experimental neurology, 2020 - Elsevier
… expression in brain-injured animals were correlated using … an effect of treatment wherein
progesterone decreased the … to reports that progesterone decreased anxiety-like behavior …

… cerebral blood flow mediates the relationship between progesterone and perceived stress symptoms among female collegiate club athletes after mild traumatic brain …

Y Chen, AA Herrold, V Gallagher… - Journal of …, 2021 - liebertpub.com
Correlation between PSS_Z of the mild traumatic brain injury (mTBI) group and progesterone
… We found high progesterone levels associated with lower or more normative stress …

Sex and estrous‐phase dependent alterations in depression‐like behavior following mild traumatic brain injury in adolescent rats

LL Giacometti, JW Huh… - Journal of neuroscience …, 2022 - Wiley Online Library
declines in circulating levels of estradiol and progesterone. … TBI in early adolescence
impacted anxiety- and depression-… use in women was correlated with less severe symptoms …

The role of estradiol in traumatic brain injury: mechanism and treatment potential

E Kövesdi, E Szabó-Meleg, IM Abrahám - International journal of …, 2020 - mdpi.com
… A negative correlation between the circulating E2 level and the size of … and progesterone
receptors [233]. Tibolone metabolites acting on both the ERα and ERβ reduce oxidative stress …

[HTML][HTML] Traumatic brain injury in women across lifespan

MO Blaya, AP Raval, HM Bramlett - Neurobiology of disease, 2022 - Elsevier
… a clear positive correlation in the … brain injury during the luteal (high progesterone) phase
of her menstrual cycle or during daily use of a progesterone OC, she had significantly reduced

GABAA receptor and serotonin transporter expression changes dissociate following mild traumatic brain injury: influence of sex and estrus cycle phase in rats

LC Fox, JL Scholl, MJ Watt, GL Forster - Neuroscience, 2023 - Elsevier
… Varying levels of endogenous estradiol and progesterone in women may be partially … to
enhanced glutamatergic output to the CeA and thus reduce anxiety at the level of the DPAG and …

Progesterone attenuates the stress response in individuals with alcohol dependence and post-traumatic stress disorder–A pilot study

E Ralevski, J Newcomb, E Pisani… - Journal of dual …, 2024 - Taylor & Francis
… that progesterone can be effective in reducing stress-induced craving, anxiety and negative
… We used the Schwartz-Bayesian criterion (BIC) to select the best-fitting correlation structure …

A Perspective on Hormonal Contraception Usage in Central Nervous System Injury

H Pradhyumnan, GG Perez, SH Patel… - Journal of …, 2024 - liebertpub.com
… ) injuries such as traumatic brain injury (TBI) and spinal cord … that progesterone treatment for
five days post-injury failed to … not establish a direct correlation between cortical changes and …