[HTML][HTML] GOLM1 exacerbates CD8+ T cell suppression in hepatocellular carcinoma by promoting exosomal PD-L1 transport into tumor-associated macrophages
J Chen, Z Lin, L Liu, R Zhang, Y Geng, M Fan… - … and Targeted Therapy, 2021 - nature.com
… with anti-PD-L1 immunotherapy relieves T cell suppression and inhibits tumor growth.
Zoledronic acid (ZA) is a clinically available drug for bone metastases by targeting osteoclasts 35,…
Zoledronic acid (ZA) is a clinically available drug for bone metastases by targeting osteoclasts 35,…
[HTML][HTML] Combination of ablation and immunotherapy for hepatocellular carcinoma: where we are and where to go
K Wang, C Wang, H Jiang, Y Zhang, W Lin… - Frontiers in …, 2021 - frontiersin.org
… , support targeted therapy and immunotherapy. The combination of ablative therapy and …
immune checkpoints (programmed cell death protein-1 [PD-1] and PD-1 cognate ligand [PD-L1])…
immune checkpoints (programmed cell death protein-1 [PD-1] and PD-1 cognate ligand [PD-L1])…
[HTML][HTML] Effectiveness and safety of toripalimab, camrelizumab, and sintilimab in a real-world cohort of hepatitis B virus associated hepatocellular carcinoma patients
J Chen, X Hu, Q Li, W Dai, X Cheng… - Annals of …, 2020 - ncbi.nlm.nih.gov
… significance of programmed cell death protein-1 (PD-1)-targeted immunotherapy in Chinese
… Our findings suggest that (I) PD-1 targeted immunotherapy with toripalimab, camrelizumab, …
… Our findings suggest that (I) PD-1 targeted immunotherapy with toripalimab, camrelizumab, …
[HTML][HTML] PD-1/PD-L1 expression profiles within intrahepatic cholangiocarcinoma predict clinical outcome
L Tian, J Ma, L Ma, B Zheng, L Liu, D Song… - World journal of surgical …, 2020 - Springer
… Immunotherapy targeting the programmed cell death protein-1 (PD-1)/programmed cell death
protein ligand 1 (PD-L1) … tumor cells and CD8 + T cells were discovered in hepatocellular …
protein ligand 1 (PD-L1) … tumor cells and CD8 + T cells were discovered in hepatocellular …
Challenges of combination therapy with immune checkpoint inhibitors for hepatocellular carcinoma
… In this review, the updated data from early-phase trials of combination immunotherapy for …
targeting the programmed cell death-1 (PD-1)/programmed cell death ligand-1 (PD-L1) …
targeting the programmed cell death-1 (PD-1)/programmed cell death ligand-1 (PD-L1) …
[HTML][HTML] The CD39+ HBV surface protein-targeted CAR-T and personalized tumor-reactive CD8+ T cells exhibit potent anti-HCC activity
F Zou, J Tan, T Liu, B Liu, Y Tang, H Zhang, J Li - Molecular Therapy, 2021 - cell.com
… cells used for cellular immunotherapy. To test this possibility, we constructed the hepatitis
B virus (HBV) surface protein-specific chimeric antigen receptor T cells (HBVs-CAR-T cells) …
B virus (HBV) surface protein-specific chimeric antigen receptor T cells (HBVs-CAR-T cells) …
[HTML][HTML] Application of regulatory cell death in cancer: based on targeted therapy and immunotherapy
X Qi, Q Li, X Che, Q Wang, G Wu - Frontiers in immunology, 2022 - frontiersin.org
… Apoptosis is an active programmed cell death caused by … The apoptosis activation pathway
is diverse, including intrinsic … treatment of advanced cancers, such as renal and liver cancers (…
is diverse, including intrinsic … treatment of advanced cancers, such as renal and liver cancers (…
[HTML][HTML] Enhanced anti-PD-1 therapy in hepatocellular carcinoma by tumor vascular disruption and normalization dependent on combretastatin A4 nanoparticles and …
… , checkpoint blockade immunotherapy targeting programmed cell death protein 1 (PD-1)
has produced promising clinical efficacy in HCC patients. Nivolumab and pembrolizumab, two …
has produced promising clinical efficacy in HCC patients. Nivolumab and pembrolizumab, two …
[HTML][HTML] TIGIT and PD1 co-blockade restores ex vivo functions of human tumor-infiltrating CD8+ T cells in hepatocellular carcinoma
Z Ge, G Zhou, LC Carrascosa, E Gausvik… - Cellular and Molecular …, 2021 - Elsevier
… TIGIT is a co-inhibitory receptor, and its suitability as a target for cancer immunotherapy in
HCC is unknown. PD1 blockade is clinically effective in about 20% of advanced HCC patients. …
HCC is unknown. PD1 blockade is clinically effective in about 20% of advanced HCC patients. …
Evolving therapeutic landscape of advanced hepatocellular carcinoma
C Yang, H Zhang, L Zhang, AX Zhu… - Nature reviews …, 2023 - nature.com
… A number of innovative therapeutic approaches have been proposed, including some
fascinating combination strategies involving targeted therapies and immunotherapies that provide …
fascinating combination strategies involving targeted therapies and immunotherapies that provide …