Dexmedetomidine for prolonged sedation in the PICU: a systematic review and meta-analysis

M Daverio, F Sperotto, L Zanetto… - Pediatric Critical Care …, 2020 - journals.lww.com
dexmedetomidine in the pediatric critical care setting as an … on dexmedetomidine use for
prolonged sedation in critically ill … were relatively rare, even in younger ages, and seemed to be …

Dexmedetomidine sedation in mechanically ventilated critically ill children: a pilot randomized controlled trial

SJ Erickson, J Millar, BJ Anderson… - Pediatric Critical Care …, 2020 - journals.lww.com
Critically ill children, younger than 16 years old, requiring … ventilated children in intensive
care to alternative sedation arms … sedation practice in improving long-term outcomes for …

Efficacy and safety of dexmedetomidine for prolonged sedation in the PICU: a prospective multicenter study (PROSDEX)

F Sperotto, MC Mondardini, C Dell'Oste… - Pediatric Critical Care …, 2020 - journals.lww.com
… are limited because of small sample size, retrospective design, and single-center setting, or
… Here, we describe the use of dexmedetomidine for prolonged sedation in critically ill children

Recommendations for analgesia and sedation in critically ill children admitted to intensive care unit

A Amigoni, G Conti, A Conio, M Corno… - … , Analgesia and Critical …, 2022 - Springer
… a neurotoxic effect especially in patients younger than 3 years [20, … use of dexmedetomidine
in critically ill children refractory to … the quality of care for a prolonged time, because reinforce …

Dexmedetomidine improves cardiovascular and ventilatory outcomes in critically ill patients: basic and clinical approaches

RL Castillo, M Ibacache, I Cortínez… - Frontiers in …, 2020 - frontiersin.org
… In children younger than 1 year, inter-individual variability … Long-term use of dexmedetomidine
leads to super sensitization … Sedatives are administered to critically ill patients to alleviate …

Analgesia and sedation in critically ill pediatric patients: an update from the recent guidelines and point of view

MC Mondardini, F Sperotto, M Daverio… - European Journal of …, 2023 - Springer
safety warning for prolonged or multiple use of anesthetics and sedative medications in
children younger … terms of efficacy and safety, many aspects on dexmedetomidine remain to be …

Patient-Specific Factors Associated with Dexmedetomidine Dose Requirements in Critically Ill Children

KR Crisamore, PE Empey, JH Pelletier… - Journal of Pediatric …, 2022 - thieme-connect.com
… Higher dose needs in younger patients (<1 year) have been … [17] [56] Fourth, the common
choice of dexmedetomidine as … Efficacy and safety of dexmedetomidine for prolonged sedation

[HTML][HTML] Effect of dexmedetomidine and propofol sedation on the prognosis of children with severe respiratory failure: a systematic review and meta-analysis

Z Xiao, T He, X Jiang, F Xie, L Xia… - Translational Pediatrics, 2022 - ncbi.nlm.nih.gov
… of these drugs in critically ill children with ARF by literature … However, prolonged sedation
may also lead to adverse effects … suggested that dexmedetomidine is a better option from an …

Current state of analgesia and sedation in the pediatric intensive care unit

C Egbuta, KP Mason - Journal of Clinical Medicine, 2021 - mdpi.com
children is quite widely available [68,69], critically ill children as well as very young and/or
intellectually disabled children … effects of dexmedetomidine for prolonged sedation (≥24 h) in …

Dexmedetomidine for sedation during pediatric noninvasive ventilation

DB Eidman, CL Clauss, SA Kelly, JM Rhieu… - Respiratory …, 2022 - rc.rcjournal.com
… that dexmedetomidine use would be skewed toward younger … Whalen et al 13 defined
long-term dexmedetomidine use as > … Dexmedetomidine use in critically ill children with acute …