… static promoter architecture and dynamic feedback regulation coordinate transcriptional
burst kinetics on a genome-wide scale. Previous studies of transcriptional bursting were limited …

… DPE mutations dramatically change transcription dynamics throughout its expression domains,
… in converting enhancer activity into transcription dynamics during animal development. …

… and molecular memory in the promoter switching dynamics. Here we analytically solve a
gene … By analyzing the dynamical phase diagram of the system, we also find that molecular …

… are insufficient to describe the transcriptional dynamics of these latent HIV integrations in
the basal state and during TNF-mediated transcriptional activation. Moreover, stimulation of …

… communication regulates transcription dynamics. (A,B) Schematic for a biological model:
The upstream EP communication in the cell nucleus (A) guides the downstream transcription, …

… This expression is believed to be purely from the P2 promoter mediated by two enhancers:
a proximal enhancer located next to P2 29,34 and a distal shadow enhancer located 4.5 kb …

… same droplet and contributing to the organization and dynamics of the three-dimensional
(3D… Given that over half of the H3K4me3-marked promoter-mediated loops tethered together to …

… Although gene transcription exhibits heterogeneity, its common features allow for the … for
transcriptional dynamics. To reveal the role for regulatory factors in transcriptional modulation, …

… Until recently, the study of transcriptional regulation was … transcriptional dynamics, in part,
because of technological limitations. Observations of the discontinuous nature of transcription …

… that promoter-mediated control of … transcriptional dynamics.Potentially, decreasing the
distance between the binding sites and core promoter increases the frequency of transcriptional …