… The first study investigating BDNF in suicide examined methylation of the promoter/exon
IV regions in the brain Wernicke area of people who died by suicide and found …

… methylation is the mechanism involved in rRNA expression regulation in AD. Hence, we
sought to explore the rDNA methylation pattern of two different brain … ribosomal RNA genes are …

… disorder and SCZ Discovered hypermethylation in the promoter region of the TrkB gene, as
well … of histone 3 Lysine 27 in the brains of suicide victims compared to non-suicide controls. …

… They identified three regions that were differentially methylated in both brain areas, mapping
to the genes psoriasis susceptibility 1 candidate 3 (PSORS1C3), TAP binding protein (…

… fact that ribosomal genes coding for ribosomal RNAs (rRNAs)… reduced rRNA production,
are characteristic to suicide … and increased rRNA synthesis are observed in the brains of folate-…

… Epigenetic mechanisms associated with suicide include DNA methylation, … in brains of
those who died by suicide, including MRI and functional imaging studies of persons with suicidal …

… , more commonly, methylation, which influences cell-specific gene expression. For example,
… adrenergic receptors in multiple brain regions in depressed suicides and controls, reporting …

… The rDNA unit encodes the 45S pre-ribosomal RNA (RNA45S… other tissues such as brain
and blood [77, 78]. The majority of … [81, 82] and high suicide rates among individuals abused as …

… Consequently, the brains of suicide victims have a diminished ability to express genes …
It was proven that the CRHR1 promoter region is not methylated since it results in increased …

… gene expression and DNA methylation during brain … brains of deceased adults from the
Quebec suicide brain bank, including suicide victims who suffered from childhood abuse, suicide …