[HTML][HTML] The use of natural compounds as a strategy to counteract oxidative stress in animal models of diabetes mellitus

M Salazar-García, JC Corona - International Journal of Molecular …, 2021 - mdpi.com
Streptozotocin (STZ) is an antibiotic that produces pancreatic … in rats partially protects
pancreatic β cells against STZ [30]. … In STZ-induced diabetic rats, Chinese and Brazilian propolis

[HTML][HTML] Propolis in metabolic syndrome and its associated chronic diseases: A narrative review

F Zulhendri, M Ravalia, K Kripal, K Chandrasekaran… - Antioxidants, 2021 - mdpi.com
streptozotocin-induced diabetic rats [98,99]. Propolis also had a protective effect on pancreatic
β-cellsPropolis prevented palmitic acid toxicity of HepG2 cells by maintaining energy …

[HTML][HTML] … rescues lymphoid organs from degeneration by regulating the crosstalk between apoptosis and autophagy in streptozotocin-induced diabetic mice

G Badr, LH Sayed, HEDM Omar… - … Science and Pollution …, 2022 - Springer
… in a streptozotocin (STZ)-induced type 1 diabetes (T1D) mouse model. Three animal
groups were used: the control non-diabetic, diabetic, and BG-treated diabetic groups. STZ-induced …

Date palm fruit extract ameliorated pancreatic apoptosis, endocrine dysfunction and regulatory inflammatory cytokines in Streptozotocin-induced diabetes in rats

MH Hafez, SS Elblehi, YS El-Sayed - Environmental Science and …, 2020 - Springer
pancreatic β cells. c Diabetic control rat (DC) showing a weak insulin immunoreactivity in the
pancreatic β cellsβ cells against STZ toxicity, as indicated by reducing the hyperglycemia. …

[HTML][HTML] Ethanol extract of propolis regulates type 2 diabetes in mice via metabolism and gut microbiota

R Guan, N Ma, G Liu, Q Wu, S Su, J Wang… - Journal of …, 2023 - Elsevier
… In this study, a high-fat diet combined with streptozotocin (STZ) intraperitoneal injection
was used to establish a T2DM mice model, and T2DM mice were supplemented with EEP and …

Bee venom attenuates degenerative effects of diabetes associated with hyperlipidemia in rats.

F Zahran, A Mohamed, N Zein - Biochemistry Letters, 2021 - blj.journals.ekb.eg
… influence of STZ, which leads to β cells degradation and … histological structure and
function of pancreatic β-cells [16]. … value of bee venom and bee propolis on Larginine-induced …

[HTML][HTML] A review on oxidative stress, diabetic complications, and the roles of honey polyphenols

VR Pasupuleti, CS Arigela, SH Gan… - … medicine and cellular …, 2020 - hindawi.com
… crucial defensive pathway to protect pancreatic β-cells both physiologically and pathologically…
T2DM can be induced by streptozotocin (STZ) by damaging β-cells of islets of Langerhans …

[HTML][HTML] Onopordum acanthium L. extract attenuates pancreatic β-Cells and cardiac inflammation in streptozocin-induced diabetic rats

AY Sharef, BA Hamdi, RA Alrawi, HO Ahmad - PLoS One, 2023 - journals.plos.org
… Strptozocin (STZ) is known to have toxic effects on pancreatic β-cells and may be used as a
… of STZ as a diabetic inducer in experimental animals. Intraperitoneal injection of STZ leads …

[HTML][HTML] Phenolics from Physalis peruviana fruits ameliorate streptozotocin-induced diabetes and diabetic nephropathy in rats via induction of autophagy and …

SM Ezzat, HMI Abdallah, NN Yassen… - Biomedicine & …, 2021 - Elsevier
STZ is a broad-spectrum antibiotic that is toxic to … pancreatic β cells bringing about
degranulation and loss of the ability to secrete insulin [67], [68]. Thus, in the present investigation, …

[HTML][HTML] An overview of the evidence and mechanism of drug–herb interactions between propolis and pharmaceutical drugs

S Hossain, M Yousaf, Y Liu, D Chang… - Frontiers in …, 2022 - frontiersin.org
propolis by scavenging ROS and increased production of anti-oxidant enzymes protected
multi-organs in the body against the toxicitySTZ-induced mice compared with using propolis