Pharmacotherapy for amyotrophic lateral sclerosis: a review of approved and upcoming agents
… of bringing new treatments to market [18]. Here, we review the existing ALS pharmacology
and … Previous Phase 2 trials provided evidence to support the safety and tolerability of each …
and … Previous Phase 2 trials provided evidence to support the safety and tolerability of each …
Advances in disease-modifying pharmacotherapies for the treatment of amyotrophic lateral sclerosis
R Hergesheimer, D Lanznaster, P Vourc'h… - … on Pharmacotherapy, 2020 - Taylor & Francis
… ALS clinical trials with the new and upcoming therapeutic strategies. Once the network
among … a large, expensive, and time-consuming phase III trial possesses a promising outlook. …
among … a large, expensive, and time-consuming phase III trial possesses a promising outlook. …
[HTML][HTML] Exploring Advancements in the Treatment of Amyotrophic Lateral Sclerosis: A Comprehensive Review of Current Modalities and Future Prospects
P Hoxhaj, N Hastings, MP Kachhadia, R Gupta… - Cureus, 2023 - ncbi.nlm.nih.gov
… We used a Pubmed search strategy and specific MeSH terms for the selection of the literature
articles using the keywords "ALS," "new treatment," "treatment," and "symptomatic treatment…
articles using the keywords "ALS," "new treatment," "treatment," and "symptomatic treatment…
Amyotrophic lateral sclerosis: a neurodegenerative disorder poised for successful therapeutic translation
… intravenous formulation in the treatment of patients with ALS. … modelling which improve
the prospects for identification of … suggest strategies to address the huge unmet need for new …
the prospects for identification of … suggest strategies to address the huge unmet need for new …
[HTML][HTML] Recent advances in understanding amyotrophic lateral sclerosis and emerging therapies
LM Gittings, R Sattler - Faculty reviews, 2020 - ncbi.nlm.nih.gov
… trials for the treatment of amyotrophic lateral sclerosis. … This is an effective strategy already
used in the treatment of … further additions or exclusions of new therapies or patient populations …
used in the treatment of … further additions or exclusions of new therapies or patient populations …
Prospects for gene replacement therapies in amyotrophic lateral sclerosis
I Giovannelli, A Higginbottom, J Kirby… - Nature Reviews …, 2023 - nature.com
… for the treatment of this … strategies for ALS and describe disease-associated loss-of-function
(LoF) mutations that could represent new future targets for gene replacement strategies…
(LoF) mutations that could represent new future targets for gene replacement strategies…
Potential of cellular therapy for ALS: current strategies and future prospects
TJ Lin, KC Cheng, LY Wu, WY Lai, TY Ling… - Frontiers in Cell and …, 2022 - frontiersin.org
… Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by
… Recently, cellular therapy has been the new hope for ALS treatment by targeting multiple …
… Recently, cellular therapy has been the new hope for ALS treatment by targeting multiple …
Exploring Multiple Sclerosis (MS) and Amyotrophic Lateral Scler osis (ALS) as neurodegenerative diseases and their treatments: a review study
O Deeb, M Nabulsi - Current topics in medicinal chemistry, 2020 - ingentaconnect.com
… engagement strategies and individualization of treatment are … exploring new improved
treatment options due to side effects… timing and the possibilities of changing the treatment regimen …
treatment options due to side effects… timing and the possibilities of changing the treatment regimen …
Emerging clinical investigational drugs for the treatment of amyotrophic lateral sclerosis
L Martinez-Gonzalez, A Martinez - Expert Opinion on …, 2023 - Taylor & Francis
… during years as a therapeutic strategy for ALS is oxidative … the safety and side effects of
the new treatment but the main … increasing the possibilities to provide effective drugs for ALS. …
the new treatment but the main … increasing the possibilities to provide effective drugs for ALS. …
Pharmacological Management of Amyotrophic Lateral Sclerosis
S Mani, C Kubba, T Sharma… - Advances in …, 2020 - taylorfrancis.com
… presently being implemented for ALS treatment. To manage the … made toward the development
of new ALS therapy, from the … antioxidative methods. It further highlights the outcomes of …
of new ALS therapy, from the … antioxidative methods. It further highlights the outcomes of …