Evaluation of silica nanoparticle mediated delivery of protease inhibitor in tomato plants and its effect on insect pest Helicoverpa armigera

G Bapat, S Zinjarde, V Tamhane - Colloids and Surfaces B: Biointerfaces, 2020 - Elsevier
… and protease inhibitors (… Inhibitor (STI) is a proteinaceous protease inhibitor obtained from
soybean (Glycine max). STI binds to trypsin at the active site and acts as a competitive inhibitor

Metal-enhanced fluorescence by bifunctional Au nanoparticles for highly sensitive and simple detection of proteolytic enzyme

JH Choi, JW Choi - Nano Letters, 2020 - ACS Publications
… or concentration of the target proteolytic enzymes. In this study, for the first time, we developed
a novel proteolytic enzyme nanobiosensor that consists of Au nanoparticles (AuNPs) and …

[HTML][HTML] The other side of the corona: nanoparticles inhibit the protease taspase1 in a size-dependent manner

J van den Boom, A Hensel, F Trusch, A Matena… - Nanoscale, 2020 - pubs.rsc.org
… Unfortunately, Taspase1's catalytic activity is not affected by common protease inhibitors.
Currently, neither genetic nor specific and highly effective chemical inhibitors for this enzyme …

[HTML][HTML] Nanoparticles based on carboxymethylcellulose-modified rice protein for efficient delivery of lutein

Y Xu, XY Ma, W Gong, X Li, HB Huang, XM Zhu - Food & function, 2020 - pubs.rsc.org
… rice protease hydrolysate (RPH)–carboxymethylcellulose (CMC) nanocarriers for efficient
as carriers to prepare nanoparticles with core–shell structures for the effective delivery of lutein…

Exploiting proteases for cancer theranostic through molecular imaging and drug delivery

T Mumtaz, M Qindeel, M Tarhini, N Ahmed… - International Journal of …, 2020 - Elsevier
protease inhibitor). Cystatins are reversible, competitive inhibitors of Cathepsin B, L, and H
and inhibit … With advanced nanotechnology-based imaging, proteases are identified at the …

Current status and perspectives of protease inhibitors and their combination with nanosized drug delivery systems for targeted cancer therapy

M Rudzińska, C Daglioglu, LV Savvateeva… - Drug design …, 2021 - Taylor & Francis
… Consequently, formulating protease inhibitors with a nanoparticleprotease inhibitors expands
their potential in biomedical applications and gives the oportunity to achieve more effective

[HTML][HTML] Review of recently used techniques and materials to improve the efficiency of orally administered proteins/peptides

YHEY Ibrahim, G Regdon, EI Hamedelniel… - DARU Journal of …, 2020 - Springer
… , mucoadhesive polymers, polymeric nanoparticles, … with protease inhibitor resulted in
improved bioavailability also in the case of pulmonary delivery, and the absorption enhancement

Enhanced oral bioavailability from food protein nanoparticles: A mini review

T Zhang, L Li, S Chunta, W Wu, Z Chen, Y Lu - Journal of Controlled …, 2023 - Elsevier
… Oral absorption enhancement of arginine/lysine functionalized chitosan-casein nanoparticles
… food protein in gastric low pH and pepsin protease remains a challenge for efficient protein …

Virus-mimicking mesoporous silica nanoparticles with an electrically neutral and hydrophilic surface to improve the oral absorption of insulin by breaking through dual …

Y Zhang, M Xiong, X Ni, J Wang, H Rong… - … Applied Materials & …, 2021 - ACS Publications
… (3−5) The first is the acidity of the gastrointestinal tract and the abundant peptidases and
proteases, … proteins and protease inhibitors, (6) or encapsulate proteins into liposomes, polymer …

The interaction of graphene oxide-silver nanoparticles with trypsin: Insights from adsorption behaviors, conformational structure and enzymatic activity investigations

H Liu, C Hao, Y Zhang, H Yang, R Sun - Colloids and Surfaces B …, 2021 - Elsevier
… , but the affinity of the immobilized protease and the substrate has not been enhanced [9]. …
it can be applied effectively to enzyme immobilization. Trypsin is an important protease and an …