Sublancin protects against methicillin-resistant Staphylococcus aureus infection by the combined modulation of innate immune response and microbiota

J Li, J Chen, G Yang, L Tao - Peptides, 2021 - Elsevier
… of CXCL1 and MCP-1 chemokines in mouse peritoneal lavage and serum, we hypothesized
… in the protective ability of sublancin. The total number of leukocytes in the mouse peritoneal …

Baicalin protects mice from infection with methicillin-resistant Staphylococcus aureus via alleviating inflammatory response

T Shi, T Li, X Jiang, X Jiang, Q Zhang… - Journal of Leucocyte …, 2020 - academic.oup.com
… Whether BAI has protective effects during infection caused … -evoked innate immune response,
mouse primary peritoneal … as a positive control in our mouse model. Besides that, DXM …

TLR2, TLR4, and NLRP3 mediated the balance between host immune-driven resistance and tolerance in Staphylococcus aureus-infected mice

Z Gong, J Zhang, S Zhang, J Cao, Y Fu, X Hu… - Microbial …, 2022 - Elsevier
… tolerance is a protective regulatory mechanism formed by … After collection, the mouse sera
were incubated at 37 C for 1 h … innate immune system could not recognize PAMPs from S. …

IL-9 blockade attenuates inflammation in a murine model of methicillin-resistant Staphylococcus aureus pneumonia

W Xu, K Tian, X Li, S Zhang - Acta Biochimica et Biophysica …, 2020 - academic.oup.com
immune response in autoimmune diseases, inflammation, and infectious diseases [11,12].
Currently, whether Th9/IL-9 is involved in the immune response … that the protective function of …

Tenascin C has a modest protective effect on acute lung pathology during methicillin-resistant Staphylococcus aureus-induced pneumonia in mice

MT Meijer, AF de Vos, H Peters Sengers… - Microbiology …, 2021 - Am Soc Microbiol
Methicillin-resistant Staphylococcus aureus (MRSA) is a … TNC plays a moderate protective
role against tissue pathology … We have studied the immune response and tissue pathology …

[HTML][HTML] The attenuation of Th1 and Th17 responses via autophagy protects against methicillin-resistant Staphylococcus aureus-induced sepsis

S Zhang, X Huang, H Xiu, Z Zhang, K Zhang, J Cai… - Microbes and …, 2021 - Elsevier
… be involved in the immune response to exogenous pathogens [… in each slide from each
mouse. The lung inflammation score … In summary, autophagy played a protective role in MRSA-…

Antibiotic treatment of Staphylococcus aureus infection inhibits the development of protective immunity

M Kleinhenz, P Beesetty, C Yang, Z Li… - Antimicrobial agents …, 2022 - Am Soc Microbiol
… This raises the question of whether more delayed treatment in clinical practice would also
inhibit protective immune responses. Moreover, we tested only vancomycin in our mouse

Salvinorin A protects against methicillin resistant staphylococcus aureus-induced acute lung injury via Nrf2 pathway

S Zeng, D Chen, G Liu, Y Wu, Z Gao, Y Su… - International …, 2021 - Elsevier
… of SA on MRSA-induced murine ALI model and its underlying … MRSA-induced ALI in mice
by activating Nrf2 signaling … the protective effects of SA on MRSA-induced ALI, a mouse

[HTML][HTML] … stimulates keratinocyte innate immune responses and attenuates methicillin-resistant Staphylococcus aureus colonization in a murine skin wound infection …

S Gao, A Khan, X Chen, G Xiao, S van der Veen… - BMC microbiology, 2022 - Springer
… -adjuvanted nontoxic mutant staphylococcal enterotoxin C (mSEC) or clumping factor A (ClfA)
resulted in protective immune responses against a subsequent S. aureus challenge [24]. …

Recombinant PBP2a of methicillin-resistant S. aureus formulation in Alum and Montanide ISA266 adjuvants induced cellular and humoral immune responses with …

SS Mortazavi, S Haghighat, M Mahdavi - Microbial pathogenesis, 2020 - Elsevier
… The development of resistance in Staphylococcus aureus … both short and long term protective
immune response [22]. … Besides, 1/500 sera dilution of each mouse serum was used in …