[HTML][HTML] PURα Promotes the Transcriptional Activation of PCK2 in Esophageal Squamous Cell Carcinoma Cells

Y Sun, J Gao, Z Jing, Y Zhao, Y Sun, X Zhao - Genes, 2020 - mdpi.com
… Our results demonstrated the novel specific motifs and functions of PURα and elucidated …
and functions of PURα in ESCC cells. Meanwhile, our findings suggest that PURα regulates the …

Noncoding RNAs and their therapeutics in paclitaxel chemotherapy: mechanisms of initiation, progression, and drug sensitivity

MK Mahabady, S Mirzaei, H Saebfar… - Journal of Cellular …, 2022 - Wiley Online Library
… Overall, it appears that miRNAs that undergo upregulation in disease, lead to disease
progression, while downregulated miRNAs exert a protective role. The miRNA inhibition and …

[图书][B] The Mechanistic Role of Long Non-coding RNAs in Advanced Prostate Cancer Response to Therapy

P Pucci - 2020 - search.proquest.com
… This project has investigated whether HORAS5 has a role in CRPC response to therapy. …
Some studies have shown efficacy of cisplatin and carboplatin in CRPC, and particularly in …

[HTML][HTML] Mechanisms of taxane resistance

SM Maloney, CA Hoover, LV Morejon-Lasso… - Cancers, 2020 - mdpi.com
… its neighboring gene, Purα, whose expression inhibits cell cycle progression. Inhibition of
MA-linc1 increases PTX-induced apoptosis, which was rescued by Purα knockdown. Further, …

[HTML][HTML] Genome-wide analysis of prognostic alternative splicing signature and splicing factors in lung adenocarcinoma

YS Chang, SJ Tu, HS Chiang, JC Yen, YT Lee… - Genes, 2020 - mdpi.com
Analysis of The Cancer Genome Atlas data revealed that alternative splicing (AS) events
could serve as prognostic biomarkers in various cancer types. This study examined lung …

Investigating the role of vacuolar-ATPase (V-ATPase) in cancer

B Whitton - 2020 - eprints.soton.ac.uk
Overexpression of V-ATPase subunits is linked to cancer cell migration, invasion and
metastasis in a number of cancer types including prostate cancer (PCa). Due to expression of …

RETRACTED ARTICLE: ST6GAL2 Downregulation Inhibits Cell Adhesion and Invasion and is Associated with Improved Patient Survival in Breast Cancer

J Cheng, R Wang, G Zhong, X Chen… - OncoTargets and …, 2020 - Taylor & Francis
… and cisplatinPurα, and Olf1, are likely to act as transcriptional activators of ST6GAL2,
suggesting that ST6GAL2 transcription could be potentially activated for specific neuronal functions

[HTML][HTML] Expression profiling of human milk derived exosomal microRNAs and their targets in HIV-1 infected mothers

MA Zahoor, XD Yao, BM Henrick, CP Verschoor… - Scientific Reports, 2020 - nature.com
… Identification of HM exosomal miRNAs that play an important role in MTCT HIV-1 infection
could be critical to our understanding of transmission; however, no studies exist that can …

Expression profiling of human milk derived exosomal microRNAs and their targets in HIV‐1 infected mothers

M Atif Zahoor, BM Henrick, CP Verschoor, A Abimiku… - 2020 - digitalcommons.unl.edu
… Identification of HM exosomal miRNAs that play an important role in MTCT HIV-1 infection
could be critical to our understanding of transmission; however, no studies exist that can …