… ] to identifying long-lived synaptic proteins [32] and age- and brain region-specific changes
in synaptic protein … enriched our understanding of the molecular basis of synaptic signaling. …

Understanding the tissue-specific genetic controls of protein levels is essential to uncover
mechanisms of post-transcriptional gene regulation. In this study, we generated a genomic …

… the aim to allow detection and quantification of proteins in single cells. It is an exciting era
of “big data” that will transform medicine and increase our understanding of human biology at …

… human brain myelinome. Our contribution comprises 102 novel myelinome proteins, in addition
to 160 newly annotated proteins … us improve our understanding of the pathophysiological …

… In this sense, the objective of the present work is to contribute to a better understanding
of … Proteomics-based studies are widely used to compare and quantify protein changes in …

… , label-free quantitative proteomics identified novel plasma biomarker signatures for tumor
… milk analysis and would deliver more functional understandings. Besides the nutritional and …

… The current paradigm has shifted from Aβ deposition towards understanding the toxicity
of different Aβ forms, especially soluble Aβ oligomers [35]. Misfolded Aβ and tau may also …

… that may be used for total proteome detection. While popular, … Notably, a more complete
and higher quality transfer is seen … proteome complexity or thus enhance our understanding of …

… Herein, we perform an analysis of all unbiased explorative proteomics studies of CSF
biomarkers in AD to critically evaluate whether proteins and peptides identified in each study are …

… We characterize AD stage-associated molecular networks by profiling 14,513 proteins and
34,173 phosphosites in the human brain with mass spectrometry, highlighting 173 protein …