[HTML][HTML] Psoriasis as an immune-mediated and inflammatory systemic disease: from pathophysiology to novel therapeutic approaches

A Campanati, A Marani, E Martina, F Diotallevi, G Radi… - Biomedicines, 2021 - mdpi.com
… in psoriasis considered as a systemic inflammatory disease? … association between multiple
sclerosis and psoriasis, an … The pathogenetic mechanism is unclear; however, a recent …

[HTML][HTML] Psoriasis and systemic inflammatory disorders

T Tashiro, Y Sawada - International journal of molecular sciences, 2022 - mdpi.com
… concerns which kinds of therapeutic options are better to regulate the development of systemic
inflammatory disorders. In the underlying mechanism of psoriasis, TNF-α or IL-23 are the …

Management of psoriasis as a systemic disease: what is the evidence?

NJ Korman - British Journal of Dermatology, 2020 - academic.oup.com
… symptoms but also reduce systemic inflammation, hence … the pathophysiological relationship
between psoriasis and its … effects of systemic inflammation in moderate‐to‐severe plaque …

[HTML][HTML] Chronic inflammation as the underlying mechanism of the development of lung diseases in psoriasis: a systematic review

M Mleczko, A Gerkowicz, D Krasowska - International Journal of …, 2022 - mdpi.com
Psoriasis is a systemic inflammatory disease caused by dysfunctional interactions between
the innate and adaptive immune responses. The systemic inflammation in psoriasis may be …

[HTML][HTML] The risk of systemic diseases in those with psoriasis and psoriatic arthritis: from mechanisms to clinic

YR Woo, CJ Park, H Kang, JE Kim - International Journal of Molecular …, 2020 - mdpi.com
… versa, the possible underlying mechanism of action between … to reduce the systemic
inflammation of psoriasis, we can … the development of various autoimmune disorders. However, to …

Chronic systemic inflammatory skin disease as a risk factor for cardiovascular disease

DA Bulger, S Minhas, AA Asbeutah, S Kayali… - Current Problems in …, 2021 - Elsevier
… in systemic inflammatory disease. Here we explore the current literature on psoriasis, … is
also more than likely some overlapping mechanism intracellularly that is shared amongst these …

The association of psoriasis and hypertension: focusing on anti‐inflammatory therapies and immunological mechanisms

MY Hu, Q Yang, J Zheng - Clinical and experimental …, 2020 - academic.oup.com
… This review summarizes the mechanisms underlying the impact of systemic inflammation
on skin and arteries, and assesses the epidemiological and clinical links between psoriasis

[HTML][HTML] Role of skin and gut microbiota in the pathogenesis of psoriasis, an inflammatory skin disease

DK Hsu, MA Fung, HL Chen - Medicine in Microecology, 2020 - Elsevier
… microbiome play key roles in the pathogenesis of psoriasis. The aim of this review is to
identify a link between the microbial ecology of the gut and skin, and their relevance to psoriasis. …

Epigenetic factors involved in the pathophysiology of inflammatory skin diseases

L Möbus, S Weidinger, H Emmert - Journal of Allergy and Clinical …, 2020 - Elsevier
… (AD) and psoriasis (PSO) but … possible mechanism that could be influencing inflammation
is epigenetic regulation, but genome-wide epigenetic studies on inflammatory skin diseases

Insights into interplay of immunopathophysiological events and molecular mechanistic cascades in psoriasis and its associated comorbidities

AK Srivastava, TC Yadav, HK Khera, P Mishra… - Journal of …, 2021 - Elsevier
… the severity of other diseases, psoriasis poses itself as a systemic inflammatory disease, which
… At the same time, the global burden of psoriasis is becoming more challenging due to the …