Dermal toxicity of sulfur mustard
JP Gray, MP Shakarjian, DR Gerecke… - Handbook of Toxicology of …, 2020 - Elsevier
… an overview of the inflammatory response to dermal skin injury. … The continued assessment
of proteolytic activity in animal … in reducing inflammation and blister formation in response to …
of proteolytic activity in animal … in reducing inflammation and blister formation in response to …
Pathophysiological effects of sulfur mustard on skin and its current treatments: possible application of phytochemicals
M Hassanpour, F Hajihassani… - … Chemistry & High …, 2021 - ingentaconnect.com
… the devastating toxicity in different parts of the body [1]. The acute poisonous effects of SM
have … results in the formation of the blister coincided with a topical inflammatory response [14]. …
have … results in the formation of the blister coincided with a topical inflammatory response [14]. …
A review of toxins from Cnidaria
I D'Ambra, C Lauritano - Marine drugs, 2020 - mdpi.com
… , edemas, blister formation, myonecrosis and inflammation) [… allowed to identify 29 putative
toxins using a high throughput … blood cells and a strong proteolytic activity for substrates like …
toxins using a high throughput … blood cells and a strong proteolytic activity for substrates like …
Identification of novel antagonists against skin relevant molecular targets in mediation of itch and inflammation
A Jäger - tuprints.ulb.tu-darmstadt.de
… Secretome of treated HaCat cells significantly reduced inflammatory response of THP-1 …
intermediate filaments and are characterized by skin blistering and muscle dystrophy. EB is a …
intermediate filaments and are characterized by skin blistering and muscle dystrophy. EB is a …
New Insights into the Toxin Diversity and Antimicrobial Activity of the “Fire Coral” Millepora complanata
VH Hernández-Elizárraga, A Ocharán-Mercado… - Toxins, 2022 - mdpi.com
… 6 and 25 kDa, and a proteolytic zone was observed between 50 and … that include severe
pain, blisters, eruptions, nephrotic syndrome, … In this study, the putative toxins detected in the M. …
pain, blisters, eruptions, nephrotic syndrome, … In this study, the putative toxins detected in the M. …
Noncytotoxic roles of granzymes in health and disease
KC Richardson, K Jung, J Pardo, CT Turner… - …, 2022 - journals.physiology.org
… ; putative role in local coagulation during inflammation (144) … blistering. Elevated GzmB
was observed in human … IL-1α proteolysis by GzmB is likely involved in the activation …
was observed in human … IL-1α proteolysis by GzmB is likely involved in the activation …
Methimazole, an Effective Neutralizing Agent of the Sulfur Mustard Derivative 2-Chloroethyl Ethyl Sulfide
A Armoo, T Diemer, A Donkor, J Fedorchik… - ACS bio & med …, 2023 - ACS Publications
… toxic effects and functional group nucleophilicity. Apart from thioacids, which produced additive
toxicity, … Mustard vesicants target the basal epidermal layer, forming blisters on skin tissue …
toxicity, … Mustard vesicants target the basal epidermal layer, forming blisters on skin tissue …
New insights into the function and pathophysiology of the ectodomain sheddase A Disintegrin And Metalloproteinase 10 (ADAM10)
D Rosenbaum, P Saftig - The FEBS Journal, 2023 - Wiley Online Library
… Proteolysis is a pivotal cellular function which is mainly … A putative regulatory role is assumed
for the cytosolic part of … Pemphigus is characterized by intraepithelial blistering of the skin …
for the cytosolic part of … Pemphigus is characterized by intraepithelial blistering of the skin …
Noncytotoxic Roles of Granzymes in Health and Disease
CT Turner, DJ Granville - journals.physiology.org
… blistering. Elevated GzmB was observed in human … ; putative role in local coagulation during
inflammation … , accumulation and proteolytic activity associated with inflammation remain …
inflammation … , accumulation and proteolytic activity associated with inflammation remain …
Mechanistic underpinning of an inside–out concept for autoimmunity in multiple sclerosis
BA 't Hart, A Luchicchi, GJ Schenk… - Annals of Clinical …, 2021 - Wiley Online Library
… The putative sequence of events in this outside–in … We posit that myelin blisters are an early
feature of myelin … complete peptide against fast proteolytic degradation by association with …
feature of myelin … complete peptide against fast proteolytic degradation by association with …