… Ionization Mass Spectrometry Imaging of Cimbi-36, a 5-HT2A Receptor Agonist, with Direct Comparison to Autoradiography and Positron Emission Tomography

SC Jacobsen, NR Speth, M Xiong, MM Herth… - Molecular Imaging and …, 2021 - Springer
… was quantified in a t = 15 min brain section by quantitative DESI… raclopride and SCH23390
in rat brain sections. The compounds were well detected by MALDI-MSI, but no specific ligand

Mass spectrometry imaging identifies abnormally elevated brain l-DOPA levels and extrastriatal monoaminergic dysregulation in l-DOPA–induced dyskinesia

E Fridjonsdottir, R Shariatgorji, A Nilsson… - Science …, 2021 - science.org
… In addition, we performed a qualitative comparison of tissue … using microdialysis and positron
emission tomography (PET), … of any other endogenous ligand not having been considered. …

Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) for in situ analysis of endogenous small molecules in biological samples

H Liu, Y Pan, C Xiong, J Han, X Wang, J Chen… - TrAC Trends in Analytical …, 2022 - Elsevier
… 4A), resulting in even layer of small crystals and generation of molecular images of lipid
distributions by MALDI imaging [92]. The device was later successfully applied DHB to desalted …

[HTML][HTML] Mass spectrometry imaging in drug distribution and drug metabolism studies–Principles, applications and perspectives

JR Granborg, AM Handler, C Janfelt - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
… PET ligands (Positron Emission Tomography), … quantitative aspects where direct quantitation,
semi-quantification or establishment of limits of detection is part of an otherwise qualitative

[HTML][HTML] Sample preparation strategy for the detection of steroid-like compounds using MALDI mass spectrometry imaging: pulmonary distribution of budesonide as a …

R Zecchi, P Franceschi, L Tigli, D Amidani… - Analytical and …, 2021 - Springer
imaging technologies such as nano positron emission tomography (Nano/PET) and fluorescent
dye imaging [13]. … Furthermore, we succeeded in setting up a quantitative MSI method for …

MALDI sample preparation methods: A mini review

AA Patil, MJN Descanzo, VB Dhisale… - International Journal of …, 2024 - Elsevier
… In particular, these techniques aim to improve signal intensities, reproducibility, and detection
limits, making them suitable for both qualitative and quantitative MALDI mass analysis. …

[HTML][HTML] Monitoring dexamethasone skin biodistribution with ex vivo MALDI-TOF mass spectrometry imaging and confocal Raman microscopy

E Pena-Rodríguez, T García-Berrocoso… - International Journal of …, 2023 - Elsevier
… semiquantitative data together with qualitative images of biodistribution, which is a … Qualitative
and quantitative MALDI imaging of the positron emission tomography ligands raclopride

Spatially resolved absolute quantitation in thin tissue by mass spectrometry

V Kertesz, JF Cahill - Analytical and Bioanalytical Chemistry, 2021 - Springer
… challenges to achieving quantitative MSI with MALDI, which … Many of the quantitative
approaches outlined for MALDI-MSI … examples of quantitative and qualitative elemental imaging

Tracking and Mapping Tumor-Targeted Alkylphosphocholine Metal Analogs with Mass Spectrometry Imaging

M Xu, CP Kerr, J Weichert, Z Morris… - … Spectrometry Imaging …, 2022 - search.proquest.com
… MS has a higher resolving power compared to MALDI TOF/TOF, we are confident that the
distribution … PET-CT (positron emission tomography-computed tomography) imaging has been …

[图书][B] Introduction to Spatial Mapping of Biomolecules by Imaging Mass Spectrometry

B Shrestha - 2021 - books.google.com
… , proteomics, as well as in quantitative and qualitative molecular analyses. Such bulk tissue
… an acoustic robotic spotter for absolute quantitative MALDI imaging of rifampicin on the liver,…