Amyloid formation as a protein phase transition

TCT Michaels, D Qian, A Šarić, M Vendruscolo… - Nature Reviews …, 2023 - nature.com
… Amyloid formation often occurs under conditions in which nucleation is a key step;
consequently, it is important to understand nucleation to obtain a quantitative description of the …

Breakage of hydrophobic contacts limits the rate of passive lipid exchange between membranes

JR Rogers, PL Geissler - The Journal of Physical Chemistry B, 2020 - ACS Publications
… This realization resolves qualitative (but not quantitative) discrepancies between simulation
and … , may function in a similar way. For example, carbon nanotubes aid vesicle fusion by …

[PDF][PDF] Single-virus content-mixing assay reveals cholesterol-enhanced influenza membrane fusion efficiency

KN Liu, SG Boxer - Biophysical Journal, 2021 - cell.com
… We quantified the rate and frequency of content-mixing events that were followed by content
loss. The frequency was calculated by dividing the number of content-mixing traces that …

Mechanistic insights of host cell fusion of SARS-CoV-1 and SARS-CoV-2 from atomic resolution structure and membrane dynamics

H Chakraborty, S Bhattacharjya - Biophysical Chemistry, 2020 - Elsevier
… There are several models that describe the mechanism of membrane fusion, out of which …
of membrane fusion or stalk model proposes that the fusion starts from a point-like membrane

Lipid-Based Nanoparticle Functionalization with Coiled-Coil Peptides for In Vitro and In Vivo Drug Delivery

D Aschmann, RA Knol, A Kros - Accounts of Chemical Research, 2024 - ACS Publications
… The Altmetric Attention Score is a quantitative measure of the attention that a research article
Fusion processes such as membrane fusion are crucial for cellular survival. They facilitate …

Fifty years of the fluid–mosaic model of biomembrane structure and organization and its importance in biomedicine with particular emphasis on membrane lipid …

GL Nicolson, G Ferreira de Mattos - Biomedicines, 2022 - mdpi.com
… The lipid-to-membrane and membrane-to-membrane fusion events occur continuously in cells,
Membrane fusion is an essential part of the process of lipid delivery to specific membrane

Escaping the endosome: assessing cellular trafficking mechanisms of non-viral vehicles

E Xu, WM Saltzman, AS Piotrowski-Daspit - Journal of Controlled Release, 2021 - Elsevier
… on quantitative and qualitative methods to assess the intracellular fate of non-viral vehicles.
We describe … liposomes mainly rely on membrane fusion to escape the endosome [210]. The …

Artificial cells: past, present and future

W Jiang, Z Wu, Z Gao, M Wan, M Zhou, C Mao… - ACS nano, 2022 - ACS Publications
… The Altmetric Attention Score is a quantitative measure of the … or copolymer film formed on
a solid surface (such as a glass … Membrane fusion research from these vesicle models can …

Separation, characterization, and standardization of extracellular vesicles for drug delivery applications

D Buschmann, V Mussack, JB Byrd - Advanced drug delivery reviews, 2021 - Elsevier
… non-trivial qualitative and quantitative effects of method … by antibodies immobilized on a
solid surface, has been used … enter the cell via membrane fusion and endocytosis, larger …

Microfluidic‐based exosome analysis for liquid biopsy

B Lin, Y Lei, J Wang, L Zhu, Y Wu, H Zhang… - Small …, 2021 - Wiley Online Library
… , substantial exosome quantitative analysis has been … exosomes: receptor-ligand
membrane fusion, and receptor-… the collision of the particles and solid surfaces. Chen et al. first …