Comparative efficacy of quetiapine by dose and formulation for psychosis in schizophrenia: A systematic review and dose–response model-based network meta …

I Terao, A Yokoi, H Fukushima - Journal of …, 2023 - journals.sagepub.com
double-blind, randomized, placebo-controlled trials that compare the antipsychotic effects for
acute psychosis … Further studies evaluating the effects of QTP-ER in the low-dose range are …

Insights into the population pharmacokinetics and pharmacodynamics of quetiapine: a systematic review

L Han, JQ Gu, JH Mao, XQ Liu… - Expert Review of Clinical …, 2024 - Taylor & Francis
placebo effect added via a linear model featuring a “drift” parameter reflecting the progression
of the disease and the placebo … verified only in patients with schizophrenia. Additionally, …

[HTML][HTML] A randomized, double-blind, placebo-controlled proof-of-concept trial to evaluate the efficacy and safety of non-racemic amisulpride (SEP-4199) for the …

A Loebel, KS Koblan, J Tsai, L Deng, M Fava… - Journal of Affective …, 2022 - Elsevier
Patients meeting DSM-5 criteria for bipolar I depression were randomized to 6 weeks of
double-blind, placebo-controlled treatment with SEP-4199 200 mg/d or 400 mg/d. The primary …

[HTML][HTML] Dose-dependent efficacy of aripiprazole in treating patients with schizophrenia or schizoaffective disorder: A systematic review and meta-analysis of …

L Qian, L Xuemei, L Jitao, S Yun'Ai… - Frontiers in psychiatry, 2021 - frontiersin.org
… evidence that the difference in adverse events between high- and low-dose groups was …
compared with the placebo group, but evidence has rarely been provided for the comparison

Quetiapine dose optimisation during gestation: a pharmacokinetic modelling study

RKS Badhan, H Macfarlane - Journal of Pharmacy and …, 2020 - academic.oup.com
Objectives The second-generation antipsychotic quetiapine has been demonstrated to
undergo gestation-related changes in pharmacokinetics. This study applied pharmacokinetic …

Dosing antipsychotics in special populations of patients with schizophrenia: severe psychotic agitation, first psychotic episode and elderly patients

F Mouaffak, F Ferreri… - Expert Opinion on …, 2021 - Taylor & Francis
double-blind randomized registration studies in nonelderly … Finally, four RCTs compared
low-dose risperidone with other … [Citation93] compared risperidone with quetiapine. This was …

A brief review of quetiapine

DE Curry, BL Richards - American Journal of Psychiatry …, 2022 - Am Psychiatric Assoc
… with high-dose quetiapine than low-dose quetiapine and placebo (5). The … double-blind
RCT assessing quetiapine in patients with primary insomnia showed some benefit with low-dose

Quetiapine abuse fourteen years later: where are we now? A systematic review

AE Vento, GD Kotzalidis, M Cacciotti… - Substance Use & …, 2020 - Taylor & Francis
… The patient recovered on low-dose amisulpride, a … against the negative symptoms of
schizophrenia, with the rationale … reasons having to do with placebo responses and an effect …

Antipsychotic dose reduction and discontinuation versus maintenance treatment in people with schizophrenia and other recurrent psychotic disorders in England (the …

J Moncrieff, N Crellin, J Stansfeld, R Cooper… - The Lancet …, 2023 - thelancet.com
… progressed well, or to reduce to a very low dose, defined as the equivalent of 2 mg of …
which found that 26% of those transferred to placebo were readmitted, compared with 10% …

Examining side effect variability of antipsychotic treatment in schizophrenia spectrum disorders: a meta-analysis of variance

MS Neumeier, S Homan, S Vetter, E Seifritz… - Schizophrenia …, 2021 - academic.oup.com
… under treatment compared with control. We included double-blind, placebo-controlled, …
For example, for quetiapine we found that patients differed in their susceptibility for weight …