… This chemistry begins with a conjugate addition of 2-amino-acetophenone 201 to 5,8-quinolone
202, presumably promoted by Ce(III) chelation by the quinolone nitrogen and proximal …

… Leishmaniasis is a neglected, parasitic tropical disease caused by an … quinoline alkaloids
having structure similar to that of compound 1 and then tested these quinoline alkaloids for …

… Historically, quinolines have been utilized to treat fevers through infusions of Cinchona (…
bark alkaloid of the “fever tree” was used as the first antimalarial drug. This cinchona alkaloid, …

… Several of the quinoline- containing compounds exhibited low toxicity … quinoline- c ontaining
compounds with anti- leishmania activity. For example, a 2- s ubstitued quinoline alkaloid …

… disease, which is caused by the protozoan parasite Trypanosoma cruzi, is among the 17
neglected tropical diseases … Quinoline derivatives are known to have antiparasitic effect against …

… In the present investigation, the impact of six alkaloids of quinoline … These typical quinoline
alkaloids showed potent activity … In the present investigation, quinoline alkaloids, quinine and …

… The focus will be on the role of alkaloids in the complex … and tropical diseases, including the
neglected tropical diseases … Simple 2-alkylated quinoline alkaloids, such as chimanine B (36…

… Its treatment is usually conducted with the use of quinoline … affections of the neglected tropical
diseases, infecting millions … the alkaloid cryptolepine (88) (Fig. 37), a hybrid of indole and …

… Quinolines have been used in human medicine since the 17th … Quinoline alkaloids are also
isolated from plant species of … A known alkaloid of quinoline, camptothecin, isolated from the …

… Quinoline and isoquinoline compounds extracted from natural sources are an essential
scaffold in the development of several parasite-associated diseases, … -type alkaloid 79 isolated …