… ,4-dihydro-4-oxo-3-quinoline carboxylic acid dimer) is considered to be the potent antibacterial
… , the introduction of metal ions into drugs has significant effects on its biological activities. …

… introduction of quinine, mefloquine, and chloroquine as antimalarial, ofloxacin, and chloroxine
as antibacterial, and various other activities proved the potential of the quinoline … dimers …

… biological activity. In the last three decades, numerous quinoline and quinolone dimers were
assessed for their … Introduction of the third substituent on the amidine-group provided both …

… The new synthetic methodologies and the biological activities of the new quinoline …
Introduction … of the existing quinolones are still active area of research. Opening up new horizons …

… dimerization of HIV-1 protease by targeting the antiparallel β-sheet involving N- and C-termini
of each monomer. Several molecules behaved as pure dimerization … of 4-quinolones have …

… number of quinoline scaffolds exhibiting diverse biological activities. Despite … Finally,
quinolones, sulfonamides, tetracyclines, and … However, dimerization of quinoline at 4-position via …

… quinoline dimers (124a-b) as an anticancer agent. The compounds 124a and 124b were
assessed for their in vitro anticancer activity … Quinoline moiety can be replaced by 2-quinolone …

… have different pharmacological activities. Literature reveals that quinoline derivatives have
… N-substituted-4-quinolone were synthesized with carboxylic acid and its ester group at C- 3 …

… This review includes most known types of heterocycles fused to quinoline or its reduced …
The word quinolone in fact is derived from quina. During the last decade quinoline derivatives …

… the introduction of the flouro group at 6-position of quinoline … approach to stop the dimerization
of TLR4 throughthe … -4 of quinoline and evaluated their biological activity as anticancer. All …