[PDF][PDF] Annotated review on various biological activities of quinoline molecule
T Kaur, DD Bhandari - Biointerface Res. Appl. Chem, 2023 - biointerfaceresearch.com
… Quinoline is a heterocyclic aromatic organic compound with … This pharmacological diversity
of quinoline has attracted … In the present review, we are outlining the potential of quinoline as …
of quinoline has attracted … In the present review, we are outlining the potential of quinoline as …
A quinquennial review on recent advancements and developments in search of anti-malarial agents
TM Dhameliya, D Kathuria, TM Patel… - Current Topics in …, 2023 - benthamdirect.com
… of the compound and among the fifteen derivatives, compound (18) containing the p-ethoxyphenyl
group on … The mainstay of anti-malarial therapy is quinolinecontaining drugs such as …
group on … The mainstay of anti-malarial therapy is quinolinecontaining drugs such as …
Amide tethered 4-aminoquinoline-naphthalimide hybrids: a new class of possible dual function antiplasmodials
… already generated severe resistance against quinoline based molecules. In … compound,
8e, with monomeric heme. In a nutshell, a solution of hemin in 40% DMSO/water shows a band …
8e, with monomeric heme. In a nutshell, a solution of hemin in 40% DMSO/water shows a band …
Quinoline containing side-chain antimalarial analogs: Recent advances and therapeutic Application
MC Joshi, TJ Egan - Current Topics in Medicinal Chemistry, 2020 - ingentaconnect.com
… The free NH2 group of compound 8 was then protected using di-tertbutyldicarbonate (Boc2O)
in DCM and Et3N as a base to furnish compound 9 [28] which was further reduced by …
in DCM and Et3N as a base to furnish compound 9 [28] which was further reduced by …
Recent Updates in chemistry of quinoline analogs as potential antimalarial agent with utilization of Chem3D software
J Singh, A Chitranshi, UA Malla, P Kumar - International Journal of …, 2023 - ijphi.com
… of quinoline-sulfonamide hybrid compounds as potential antimalarial medications. These
compounds have different linker groups … with dibenzyl methylamine (dibemethin) side chains …
compounds have different linker groups … with dibenzyl methylamine (dibemethin) side chains …
Pyrido-Dibemequine Metabolites Exhibit Improved Druglike Features, Inhibit Hemozoin Formation in Plasmodium falciparum, and Synergize with Clinical …
… Moreover, the benzylamine/benzylmethylamine side groups appended to the quinoline core
can also adopt a planar conformation that would contribute to π-π interactions and potential …
can also adopt a planar conformation that would contribute to π-π interactions and potential …
Discovery and Development of Antimalarial Drug Resistance Reversal Agents
… quinoline drugs as well as the re-use of old antimalarial … (dibemethin) side chains [64, 65]
and these compounds were equally … ) and 44 (containing 3-chlorophenyl and 3-pyridyl groups). …
and these compounds were equally … ) and 44 (containing 3-chlorophenyl and 3-pyridyl groups). …
The cinchona alkaloids and the aminoquinolines
SL Rawe, C McDonnell - Antimalarial Agents, 2020 - Elsevier
… The bark also contains numerous minor quinoline derivatives including quinicine (5) (also …
which the chloro group was at position 6 of the quinoline ring resulted in a compound that was …
which the chloro group was at position 6 of the quinoline ring resulted in a compound that was …
[HTML][HTML] Functionalized 3-hydroxy-3-aminoquinoline-oxindole hybrids as promising dual-function anti-plasmodials
B Sharma, J Legac, N Cele, P Awolade… - European Journal of …, 2022 - Elsevier
… Our research group recently reported that … the quinoline's potency against the highly
resistant strain [37,38]. The design of present set of scaffolds is based on integrating the quinoline …
resistant strain [37,38]. The design of present set of scaffolds is based on integrating the quinoline …
[HTML][HTML] Biological evaluation of novel side chain containing CQTrICh-analogs as antimalarials and their development as PfCDPK1 kinase inhibitors
… Quinoline antimalarials containing a dibemethin group are active against chloroquinone-resistant
plasmodium falciparum and inhibit chloroquine transport via the P. falciparum …
plasmodium falciparum and inhibit chloroquine transport via the P. falciparum …