Discovery, Topo I inhibitory activity and mechanism evaluation of two novel cytisine-type alkaloid dimers from the seeds of Sophora alopecuroides L

C Meng, Y Wang, S Chen, M Li, C Yuan… - Bioorganic & Medicinal …, 2022 - Elsevier
… monomeric alkaloids, dimeric quinolizidine alkaloids are … new quinolizidine alkaloid dimer
showed better anti-inflammatory effects than matrine, proving that the pharmacological activity

Integrated transcriptome and small RNA sequencing analyses reveal a drought stress response network in Sophora tonkinensis

Y Liang, K Wei, F Wei, S Qin, C Deng, Y Lin, M Li… - BMC Plant …, 2021 - Springer
tonkinensis have shown that quinolizidine alkaloids and flavonoids are the … tonkinensis,
acts as the main medicinal active ingredient and has been proven to have anti-inflammatory, …

Molecular mechanism of the anti-inflammatory effects of Sophorae Flavescentis Aiton identified by network pharmacology

N Zhu, J Hou - Scientific reports, 2021 - nature.com
… Isosophocarpine, a tetracyclic quinolizidine alkaloid, shows anti-cancer effects on different
types of cancer by attenuating inflammation 29 . Quercetin is a flavonoid with antioxidant, …

Oxymatrine: A current overview of its health benefits

DQ Huan, NQ Hop, NT Son - Fitoterapia, 2023 - Elsevier
… condition because of its anti-inflammatory (downregulation of cytokine mRNA, and … analysis
of quinolizidine alkaloids and their biosynthetic precursor, lysine, in Sophora alopercuroides …

Research progress on antibacterial activities and mechanisms of natural alkaloids: A review

Y Yan, X Li, C Zhang, L Lv, B Gao, M Li - Antibiotics, 2021 - mdpi.com
… into simple pyridine alkaloids, quinolizidine alkaloids, and indolizidine alkaloids [8]. These
… glycoside alkaloids were isolated from Sophora tonkinensis. Antibacterial activity screening …

[引用][C] Quinolizidine Alkaloids from Sophora tonkinensis and Their Anti-Inflammatory Activities

F Roufosse, J Kahn, ME Rothenberg, AJ Wardlaw… - J. Allergy Clin. Immunol, 2020

Exploring the potential role of genus Sophora in the management of osteoporosis: a phytochemical and biological review

SH Aly, AMM Elbadry, M El-Shazly… - Frontiers in Natural …, 2023 - frontiersin.org
activities due to their anti-inflammatory, antioxidant, and anti-cancer effects, as well as their
ability … Oxymatrine (OMT) is a quinolizidine alkaloid isolated from Sophora medicinal plants. It …

Monoterpenoid indole alkaloids from the fruits of Gelsemium elegans and their anti-inflammatory activities

NP Li, JS Liu, JW Liu, HY Tian, HL Zhou, YR Zheng… - Bioorganic …, 2021 - Elsevier
… Therefore, we preliminarily evaluated the anti-inflammatory activities of compounds 1–6 in
… 1–3 exerted anti-inflammatory effects. The anti-inflammatory activities of these compounds …

Optimization of Extraction Technology of Sophora Tonkinensis Gagnep. by Orthogonal Test Based on Information Entropy Weighting Method

Y Wang, H Zhang, P Zhang, J Lan, H Chen… - … Conference, BigIoT-EDU, 2022 - Springer
… , flavonoids, polysaccharides, etc., Among them, alkaloids are the … the alkaloids of Radix
Sophorae have anti-inflammatory properties [7], antiviral [8], Antibacterial [9] And other activities. …

Anti-Tumor Activities of Bioactive Phytochemicals in Sophora flavescens for Breast Cancer

X Cao, Q He - Cancer management and research, 2020 - Taylor & Francis
… As one of the major quinolizidine alkaloids of Sophora flavescens, MT (C 15 H 24 N 2 O) is
… -asthma, anti-bacterial, anti-inflammatory and immune suppressive activities. What’s more, it …