… Here, we show that G3BP, a phosphorylation-dependent endoribonuclease that interacts
with … G3BP may thus determine the fate of mRNAs during cellular stress. Remarkably, SG …

… condensation may contribute to neurodegenerative disease (Wolozin and Ivanov, 2019),
we next tested whether G3I compounds would affect stress granule assembly and/or …

… ) showing that the G3BP1 phosphomimetic mutant construct (pEGFP-C1-G3BP1-S149E) …
to support the conclusion that G3BP1 regulates stress granule assembly and that Ras signaling …

… To delve deeper into the role of PARP10 in G3BP1-mediated SG assembly, we transfected
the G3BP1/2 dKO cell line with either PARP10 siRNA or non-targeting siRNA (siCon), then …

… of G3BP1-S149 does not influence stress granule assembly”(Panas et al., 2019. J. Cell
Biol. … -C1-G3BP1-S149A and S149E constructs and the 1–168 truncations of GFP-G3BP1-S149A …

… , which is critical for cancer cell survival during stress through RNA binding activity of G3BP1.
… High expression of SGs-nucleating proteins such as G3BP1 can promote SGs assembly. …

… The stress granule discussed in this review refers to the previously mentioned cytoplasmic
stress granule… While G3BP1 has an antiviral effect in stress granules, it is now clear that direct …

… stress granules assembly even in stress-null con-ditions[34,35]. The Arg-Gly-Gly (RGG) motif
of UBAP2L plays a key role in SGs assembly[… the role of G3BP1 in SGs assembly, its role in …

… G3BP1, could induce SG formation even without stress conditions.7 As the key regulator of
SG assembly, G3BP1 … It is elucidated that the enhancement of G3BP1 translation induces SG …

… of stress granules, the punctate protein–RNA assemblies that form … stress granule cores that
act independently of G3BP1 and … As the substrate was retracted from the solution, beads of …