… We discuss the cellular mechanisms resolving these threats … the [protein-bridged] interstrand
cross-links induced in DNA by … 1995 Radiation-induced DNA damage in tumors and normal …

… The mechanisms underlying ionizing radiation-induced DPC … DNA ends correlates with its
evolutionally conserved role in … agent-induced TOP-DNA cross-links in T4 bacteriophages was …

… , cross-linked proteins are … DNA-peptide cross-links are eliminated in various DNA repair
pathways. Delineating the molecular mechanisms of DHC repair would help target specific DNA …

… mechanism to repair them. Indeed, many different enzymes have been shown to act on DPCs
by either processing the protein, the DNA or … knowledge on the mechanisms of replication-…

… The mechanisms for radiation induced cancers will also be … It has been suggested that
this pathway may have biological significance … (4-HNE) can induce interstrand DNA cross-links. …

… sensitized DNA as well as the formation of extremely lethal interstrand cross-links. We
observed previously described mechanisms related to photoinduced electron transfer leading to …

… the protein and DNA after radiation-induced generation of DNA … transcription mechanisms
require a separation of the DNA … sites, cross-links, and effect on DNA-binding proteins, the …

… Finally, a role for NEIL3 in the repair of interstrand DNA-DNA cross-links (ICLs) has been
defined. It was first shown by the Walter’s lab in Xenopus egg extracts (Semlow et al. Citation…

… understanding of the molecular mechanisms involved in DPC resolution. Two proteolytic
repair pathways have emerged in recent years as essential mechanisms for coping with DPCs (…

… Broadly, enzymatic mechanisms of DPC formation result … of nearby proteins, resulting in
the formation of a DNA protein … proteins [36,37]. Similarly, ionizing radiation induces unstable …