Aptamer-based technology for radionuclide targeted imaging and therapy: A promising weapon against cancer

L Filippi, O Bagni, C Nervi - Expert Review of Medical Devices, 2020 - Taylor & Francis
… of radiolabeled aptamers for the in vivo imaging of several … , and amplification of the nucleic
acid pool through PCR. A … emitting both positrons for PET imaging and beta-particles for …

[HTML][HTML] Application of aptamer-functionalized nanomaterials in molecular imaging of tumors

X Yin, H Zhao, Z He, X Wang - Nanotechnology Reviews, 2023 - degruyter.com
… targeting ability of nucleic acid aptamers but also have the … was modified with other
disease-specific aptamers and could … the imaging agent 64 Cu@LCI-Apt with good radiolabeling

Development and classification of RNA aptamers for therapeutic purposes: an updated review with emphasis on cancer

M Razlansari, S Jafarinejad, A Rahdar… - Molecular and Cellular …, 2023 - Springer
… tool for developing effective disease-specific probes. Cell-… the acting time of nucleic acid
aptamers. PEGylation reduces … These radiolabeled aptamers rapidly penetrated the tumor …

[HTML][HTML] Nanomaterial probes for nuclear imaging

VJX Phua, CT Yang, B Xia, SX Yan, J Liu, SE Aw, T He… - Nanomaterials, 2022 - mdpi.com
nucleic acids such as aptamers have been attracting interest as targeting moieties. Several
reports showed aptamers have a highhigh affinity for 68 Ga radiolabeling for PET imaging, …

Aptamers, the nucleic acid antibodies, in cancer therapy

Z Fu, J Xiang - Advances in Medical Biochemistry, Genomics …, 2021 - api.taylorfrancis.com
… Single-stranded nucleic acid molecules can bind to complementary … , S., Veedu, RN
Radiolabeling 134 of nucleic acid aptamers for highlydisease-specific molecular imaging. …

Recent advances in aptamer-based nanomaterials in imaging and diagnostics of cancer

P Sa, SK Sahoo - Aptamers Engineered Nanocarriers for Cancer …, 2023 - Elsevier
… , aptamers have significantly advanced the molecular imagingaptamers can be used as
useful tools for highly sensitive cell … It is speculated that radiolabeled aptamers would have great …

[HTML][HTML] Discovery of cell-internalizing artificial nucleic acid aptamers for lung fibroblasts and targeted drug delivery

H Uemachi, Y Kasahara, K Tanaka, T Okuda… - Bioorganic …, 2020 - Elsevier
… instead of the cell line in the positive selection may present more disease-specific aptamers.
imaging probe by chemical conjugation with chelating or radiolabeled agents to aptamers […

[HTML][HTML] Diagnostics and therapeutics in targeting HER2 breast cancer: a novel approach

C Vi, G Mandarano, S Shigdar - International Journal of Molecular …, 2021 - mdpi.com
… radiolabelled aptamers can achieve highly sensitive and specific real-time molecular imaging
for … [124] modified the aptamers into PET imaging agents by radiolabelling HeA2_1 and …

RNA nanostructures for targeted drug delivery and imaging

L Teodori, M Omer, J Kjems - RNA biology, 2024 - Taylor & Francis
… offer a more efficient radiolabeling of nucleic acids with radionuclides … RNA aptamer targeting
the extracellular domain of EGFR, chemically coupled to 18 F-fluorobenzyl for PET imaging

Aptamers as versatile ligands for biomedical and pharmaceutical applications

B Guan, X Zhang - International journal of nanomedicine, 2020 - Taylor & Francis
… , which indicated that Sgc8-FSNPs were a highly sensitive … (A) with a demonstration of PET
molecular imaging for HER2 in … One approach is to utilize disease-specific aptamers with high