… activity of Rai as a negative regulator of TCR and BCR signaling, it has been observed that
… differentiation and autoimmunity The ability of Rai to fine-tune the antigen receptor signaling …

… conditions like autoimmunity and infectious disease. … P2Y6 as a negative regulator of NK
cell maturation and function [80]. Among … In addition, the T cell activation via P2X7R inhibits the …

… in the pathogenesis of several autoimmune and immune-… specific phosphatase that inhibits
T cell signaling through … negative regulator of T-cell activation during the presentation of …

… autoimmune process is the regulation and control of local inflammatory cytokines production.
The deteriorating effects of autoimmune … of insulin signaling through the inhibition of IRS-1 …

… antigens to T lymphocytes, thereby inducing T-cell activation. … , these activated T cells
might target the heart in an autoimmune-… functions in order to inhibit the maturation and T-cell …

… negative regulators of G protein function and RhoG. ARHGDIG or Rho-GDP-dissociation
inhibitor-3 inhibits … against immunological disorders such as autoimmune diseases and other …

… or IL-17 also they skewed autoimmune response. The up and … pathways involved in T-cell
activation and how aging alters … cancer cell growth using immune checkpoint inhibitors. Few …

… B cell activation and the aberrant signaling downstream of … A diverse antigen receptor
repertoire is generated by the unique … It is established that PTPN22 is a negative regulator of SRC-…

… protein Rai is a negative regulator of T cell receptor signaling … hyperactive phenotype of T
cells in autoimmune diseases. … suppresses TCR signaling and T cell activation, together with …

… A second costimulatory signal is required for T-cell activation, … TSH receptor (TSHR) antibodies
(TSHR-Ab) blocking TSH … to RAI-induced cytolytic effect and release of thyroid antigens, …