… antigen receptor (… function as negative regulators of T-cell activation [166]. In 2011, the first
antibody-based immune checkpoint blockade (ICB) treatment, ipilimumab (a CTLA-4 inhibitor)…

… 1), Epstein-Barr virus, and autoimmune disorders, have been … of mature lymphocytes with
effective antigen receptors (65). … -cell activation, the expression of CD38 and CD69 on the cell …

… Current limitations in using chimeric antigen receptor T(CART… –mediated autoimmunity, we
studied the effects of inhibiting … 45% of patients with CLL of Rai stages 0 and 1 exceeded this …

… , monomeric IgM is part of the B cell antigen receptor (BCR) [2], … immunity and regulation of
autoimmune processes by … , including IGHV mutational statuses and Rai stages. Serum FcµR …

… in the development of autoimmune or autoinflammatory … The AIM2-induced GSDMD
functions as a negative regulator … antigen presenting cell activation and maturation, indirect NK …

… antigen receptor that recognizes a disease-relevant antigen (… To this end, the inhibition of
Foxp3 negative regulators … suppressive function in experimental models of autoimmunity and …

… efficacy of DC and chimeric antigen receptor T-cell vaccines will be … pathways that ward off
autoimmunity during immune responses … We posit that blocking either regulator T cells or their …

… and is being widely used to treat certain autoimmune conditions, such as multiple sclerosis
(… function of Ifit2 in autoimmune inflammation in part by modulating myeloid cell function and …

… therapies, including chimeric antigen receptor T cell (CAR-T) … to CRS and that blocking an
individual cytokine or … To test the mechanisms of how RAI contributes to T cell activation, we …

… In our opinion, Particular autoimmune models and … ) ligand 9(CXCL9) and B cell activating
factor (BAFF) from B cells … to Tregs with chimeric antigen receptor (CAR)technology, providing …