[HTML][HTML] Changes in serum estrogenic activity during neoadjuvant therapy with letrozole and exemestane

N Bahrami, G Chang, N Kanaya, T Sauer… - The Journal of Steroid …, 2020 - Elsevier
… drugs (anastrozole, letrozole and exemestane) have been … of patients without any differences
between the two AIs used in … A phase II trial conducted by the Hellenic Group of Oncology (…

Superior suppression of serum estrogens during neoadjuvant breast cancer treatment with letrozole compared to exemestane

BE Bertelsen, B Almås, K Fjermeros, K Viste… - Breast Cancer Research …, 2024 - Springer
… In this report, we present the results of a phase II neoadjuvant trial, performed at the …
comparison between the two non-steroidal AIs and direct competitors, anastrozole and letrozole, …

Neoadjuvant everolimus plus letrozole versus fluorouracil, epirubicin and cyclophosphamide for ER-positive, HER2-negative breast cancer: a randomized pilot trial

W Wu, J Chen, H Deng, L Jin, Z He, N Rao, Y Nie… - BMC cancer, 2021 - Springer
… Baseline tumor Ki67 index showed no statistical differences between NET and NAC groups
(P … Therefore, in our future randomized controlled phase II or III trial with larger sample size, a …

… recurrence after neoadjuvant endocrine therapy: data from ACOSOG Z1031 (Alliance), a randomized phase 2 neoadjuvant comparison between letrozole, anastrozole …

KK Hunt, VJ Suman, HF Wingate, AM Leitch… - Annals of surgical …, 2023 - Springer
… ) Z1031 was a randomized phase 2 neoadjuvant clinical trial … either exemestane (2.5 mg
daily), anastrozole (1 mg daily), or … The ALTERNATE (Alternate Approaches for Clinical Stage II

… With Estrogen Receptor–Rich/ERBB2-Negative Breast Cancer Receiving Neoadjuvant Anastrozole, Fulvestrant, or Their Combination: A Phase 3 Randomized …

CX Ma, VJ Suman, S Sanati, K Vij, M Anurag… - JAMA …, 2024 - jamanetwork.com
… Postmenopausal women with clinical stage II to III, ER-rich (Allred score 6-8 or >66%)/ERBB2-negative
breast cancer were included. All analyses were based on data frozen on March 2…

[HTML][HTML] … or anastrozole in oestrogen receptor-positive, HER2-negative, early breast cancer (coopERA Breast Cancer): an open-label, randomised, controlled, phase 2 …

SA Hurvitz, A Bardia, V Quiroga, YH Park… - The Lancet …, 2023 - thelancet.com
… ), aromatase inhibitors (eg, letrozole, anastrozole, and exemestane), and the first-generation …
versus anastrozole corresponded to an effect size of 0·3 (ie, the difference between two

Extended therapy with letrozole as adjuvant treatment of postmenopausal patients with early-stage breast cancer: a multicentre, open-label, randomised, phase 3 trial

L Del Mastro, M Mansutti, G Bisagni, R Ponzone… - The Lancet …, 2021 - thelancet.com
… A randomized trial of exemestane after two to three years of … , previous adjuvant or neoadjuvant
chemotherapy, and body-… 10 years showed no differences between the two groups. 5-…

The landmark series: neoadjuvant endocrine therapy for breast cancer

A Weiss, TA King, EA Mittendorf - Annals of Surgical Oncology, 2020 - Springer
… , and letrozole and anastrozole are superior to exemestane. … different durations of
neoadjuvant treatment with letrozole in … or partial response to neoadjuvant letrozole as well as to …

Efficacy of alternative dose regimens of exemestane in postmenopausal women with stage 0 to II estrogen receptor–positive breast cancer: a randomized clinical trial

D Serrano, S Gandini, P Thomas, KD Crew… - JAMA …, 2023 - jamanetwork.com
… a phase II trial … difference between the once-daily and 3-times-weekly arms. The PgR
reduction was identified in this presurgical study and in different neoadjuvant studies of exemestane

Phase II single-arm study of preoperative letrozole for estrogen receptor–positive postmenopausal ductal carcinoma in situ: CALGB 40903 (Alliance)

ES Hwang, T Hyslop, LH Hendrix, S Duong… - Journal of Clinical …, 2020 - ascopubs.org
Differences among treatment groups were evaluated using Fisher’s … to neoadjuvant therapy
in invasive cancer. We found that the majority of MRI changes were seen early in letrozole