… of erlotinib 100 mg/d vs. gefitinib 250 mg/d in EGFR-mutated advanced non-small cell lung cancer (E100VG250): an open-label, randomized, phase 2 study

S Zhao, Z Zhang, W Fang, Y Zhang, Z Zhang… - Frontiers in …, 2020 - frontiersin.org
… in EGFR-mutated advanced NSCLC. Therefore, to properly addressed this problem, we
designed this randomized, phase-2 study comparing the efficacy and tolerability of erlotinib 100 …

[HTML][HTML] A randomized phase 2 study of gefitinib with or without pemetrexed as first-line treatment in nonsquamous NSCLC with EGFR mutation: final overall survival …

JCH Yang, Y Cheng, H Murakami, PC Yang… - Journal of Thoracic …, 2020 - Elsevier
… conducted a randomized phase 2 study to explore the clinical benefits of adding pemetrexed
to gefitinib in patients with advanced … The primary analysis of this study showed a significant …

… survival analysis of the randomized phase 2 trial of erlotinib versus gemcitabine plus cisplatin as neoadjuvant treatment of stage IIIA-N2 EGFR-mutant nonsmall cell …

YL Wu, W Zhong, KN Chen, C Chen, F Yang, XN Yang… - 2021 - ascopubs.org
study. Methods: This was a multicenter (17 centers in China) phase II randomized controlled
trial of erlotinib… as neoadjuvant/adjuvant therapy in pts with stage IIIA-N2 NSCLC with EGFR …

[HTML][HTML] Apatinib plus gefitinib as first-line treatment in advanced EGFR-mutant NSCLC: the phase III ACTIVE study (CTONG1706)

H Zhao, W Yao, X Min, K Gu, G Yu, Z Zhang… - Journal of thoracic …, 2021 - Elsevier
… , randomized, placebo-controlled phase 2 study 26 on advanced NSCLC after two lines of
… Systemic therapy for locally advanced and metastatic non-small cell lung cancer: a review …

Combination of gefitinib and olaparib versus gefitinib alone in EGFR mutant non-small-cell lung cancer (NSCLC): A multicenter, randomized phase II study (GOAL)

R Garcia-Campelo, O Arrieta, B Massuti… - Lung Cancer, 2020 - Elsevier
… a multicenter, randomized phase IB/II study performed in two countries, Spain and Mexico.
Eligible patients were 18 years or older, treatment-naïve, pathologically confirmed stage IV …

[HTML][HTML] Gefitinib as neoadjuvant therapy for resectable stage II-IIIA nonsmall cell lung cancer: A phase II study

Y Zhang, F Fu, H Hu, S Wang, Y Li, H Hu… - The Journal of Thoracic …, 2021 - Elsevier
study aimed to investigate the efficacy and safety of preoperative gefitinib in patients with
stage II-IIIA operable nonsmall … whereas patients were enrolled with stage II or IIIA in our study

… therapy in unresectable stage III epidermal growth factor receptor mutation-positive non-small cell lung cancer: a multicenter, randomized, open-label, phase 2 trial

L Xing, G Wu, L Wang, J Li, J Wang, Z Yuan… - International Journal of …, 2021 - Elsevier
randomized phase 2 trial has compared erlotinib + RT and CCRT in patients with EGFRm-positive
unresectable stage … In a phase 2 study by Lee et al, 12 which compared E + RT versus …

… From Randomized, Phase II EVAN Study of Erlotinib Versus Vinorelbine Plus Cisplatin Adjuvant Therapy in Stage IIIA Epidermal Growth Factor Receptor+ NonSmall …

D Yue, S Xu, Q Wang, X Li, Y Shen, H Zhao… - Journal of Clinical …, 2022 - ascopubs.org
… chemotherapy) trials, 12 erlotinib potentially prolonged the 5-year DFS in the … study
population compared with gefitinib. Another recent phase II study of adjuvant erlotinib for patients

Low-dose erlotinib treatment in elderly or frail patients with EGFR mutation–positive nonsmall cell lung cancer: A multicenter phase 2 trial

S Miyamoto, K Azuma, H Ishii, A Bessho… - JAMA …, 2020 - jamanetwork.com
… First-line gefitinib for patients with advanced nonsmall-cell lung cancer harboring …
multicenter phase 2 clinical trial to investigate the efficacy and safety of low-dose erlotinib in …

Randomized Phase III Study of Gefitinib Versus Cisplatin Plus Vinorelbine for Patients With Resected Stage II-IIIA NonSmall-Cell Lung Cancer With EGFR Mutation …

H Tada, T Mitsudomi, T Misumi, K Sugio… - Journal of Clinical …, 2022 - ascopubs.org
… In conclusion, gefitinib as postoperative adjuvant therapy for patients with resected stage
II-III NSCLC harboring EGFR mutations was not beneficial in prolonging DFS and OS. Thus, …