… The standard of care for the adjuvant treatment of stage II/III colon cancer … alone to adjuvant
FOLFOX (infusional 5‐FU, leucovorin, and oxaliplatin) based on two large randomized trials …

… resectable gastric cancer compared with surgery alone in 2 phase 3 randomized clinical trials
(RCTs)… Although cisplatin plus S-1 did not demonstrate superiority to cisplatin plus infusion …

… Patients with chemo-naive, metastatic PDAC were eligible to receive fixed-rate infusion (10
mg/m 2 /… A randomised phase II trial comparing SLOG versus modified FOLFIRINOX in locally …

… biweekly regimen of IP paclitaxel and FOLFOX is safe and the recommended dose of IP
paclitaxel for a phase II trial … of 5-fluorouracil continuous infusion vs. sequential methotrexate and …

… In the 1980s, 5-fluorouracil–leucovorin (5-FU/LV) therapy … surgery following randomized
clinical trials comparing several … ) trial [14, 15] revealed that adding oxaliplatin to biweekly LV/5-…

… The treatment was consisted of biweekly gemcitabine 800 mg/m 2 , 10 mg/m 2 /min infusion
… including liposomal irinotecan plus 5-fluorouracil/leucovorin in 20 patients, nab-P + Gem in 5…

… Weekly 5-FU–leucovorin with biweekly bevacizumab may be … combination with oral or
infusional fluoropyrimidine in such … the cross-trial comparison above, especially for clinical trials for …

… hour continuous infusion once every two weeks. … only studies comparing monotherapy
versus oxaliplatin- or irinotecanbased doublets14,15 and the more recent phase III RESPECT trial …

… The RAMIRIS trial is a randomized, open-label, multicenter phase II/III study comparing …
(Arm A) or paclitaxel 80 mg/m 2 (days 1, 8, 15, q28) with ramucirumab 8 mg/kg every two weeks (…

… administered every two weeks for 4 cycles and Spartalizumab every four weeks for 2 cycles.
… Spartalizumab (PDR001): patients will receive the fixed dose of 400 mg per IV infusion over …