… Using our murine model, we identify alveolar macrophages as a key … Rapid host
defense against Aspergillus fumigatus involves alveolar macrophages with a predominance …

… role in host defense against aspergillosis and induces … of phagocytic cells (8) and involves
the assembly and formation of a … result in a higher lung fungal burden or in more rapid disease …

… Aspergillus section Fumigati includes 63 species and the … ) contribute to the innate host
defence in vivo and neutrophils exert a … are killed by local alveolar macrophages, and has been …

… aspect in initiating host defence mechanisms. Ungerminated … MΦ subset appear to be involved
in resolving inflammation [70]… Killing of Aspergillus fumigatus by alveolar macrophages is …

… It has been confirmed that TLR2 and TLR4 are involved in sensing fungal DNA and …
fumigatus in mice alveolar macrophages, and is required for the induction of alveolar macrophage …

… a Th2-type adaptive immune response involving the release of IL-4, … aeruginosa with an
incredible capacity to adapt rapidly to … fumigatus, a finding supported by the predominance of the …

… Alveolar macrophages are critical for killing inhaled conidia and … fumigatus spores are rapidly
engulfed and killed by host … β-1,3-glucans [65] are involved in the induction of the type I IFN …

… In healthy hosts, the inhaled conidia are rapidly eliminated … , but it is not involved in the
pathogenicity of A.fumigatus. The … A.fumigatus are alveolar macrophages (AM) and neutrophils. …

… factors of Aspergillus, antifungal host defences including innate … fluid are involved in
Aspergillus defense including pathogen … fumigatus is intact in alveolar macrophages even in the …

… -resident macrophages comprise the first line of defense … tract are rapidly emerging, but
still much remains to be learned. … known to be involved in the antifungal defenses against A. …