… This study sought to evaluate the effect of the interleukin-6 … In the ASSAIL-MI trial, we
randomized 199 patients with acute ST-… For safety reasons, we excluded patients with a time from …

… In this predefined exploratory sub-study of the ASSAIL-MI trial we examined the effect of …
Rationale for the ASSAIL-MI-trial: a randomised controlled trial designed to assess the effect of …

… With the ASSAIL-MI trial, we show that a single dose of tocilizumab significantly increased …
Rationale for the ASSAIL-MI-trial: a randomised controlled trial designed to assess the effect of …

… ASSAIL-MI trial: to describe the rationale and design of the ASSAIL-MI trial, to investigate the
effect … In the ASSAIL-MI trial, our main objective was to assess the effect of IL-6 inhibition in …

… The purpose of this study was to evaluate the effect of tocilizumab on … The design of
ASSAIL-MI has been published previously. … In this substudy of the ASSAIL-MI trial, we show that …

… AMI induces a pro-inflammatory state, the primary purpose of which … investigations such as
the ongoing ASSAIL-MI trial [65]. … the anti-inflammatory effects of several immunomodulatory …

… and showing their design as well as their … effect for anti-inflammatory therapy than the
STEMI patients included in VCU-ART3. Following the same rationale, the recent ASSAIL-MI trial …

… used a random-effects model to assess the pooled treatment effect. … One reason for this
could be that the risk of MI is higher in … In the ASSAIL-MI trial, tocilizumab increased myocardial …

… among patients with acute STEMI in the ASSAIL-MI trial [52]. … larger controlled studies to fully
examine their impact on clinical … For this purpose, the use of the dietary inflammatory index (…

… For these reasons, researchers moved to IL-6; they found that … Next, researchers designed
a clinical trial to evaluate the effect … ), and this clinical trial is called the ASSAIL-MI trial. The …