Nanomedicine-driven molecular targeting, drug delivery, and therapeutic approaches to cancer chemoresistance

VM Khot, AB Salunkhe, S Pricl, J Bauer, ND Thorat… - Drug Discovery …, 2021 - Elsevier
… (MRI) to overcome cancer chemoresistance via tailored ferroptotic … A size-shrinkable
gelatin-based molecular nanovehicle that … Although conceptually ideal for rational design, …

The reversal of chemotherapy-induced multidrug resistance by nanomedicine for cancer therapy

S Liu, AR Khan, X Yang, B Dong, J Ji, G Zhai - Journal of Controlled …, 2021 - Elsevier
… the resistant cancer cells and plays a crucial role in extruding structurally unrelated chemotherapy
agents … the overexpressed P-gp is a straightforward strategy to overcome cancer MDR. …

Rational nanocarrier design towards clinical translation of cancer nanotherapy

D Guo, X Ji, J Luo - Biomedical Materials, 2021 - iopscience.iop.org
… drug delivery and cancer treatments. Further, we review the strategies for rational design
of … translation in enhancing cancer treatment via both chemotherapy and immunotherapy. …

Nanomedicines for combating multidrug resistance of cancer

YX Zhu, HR Jia, QY Duan, FG Wu - Wiley Interdisciplinary …, 2021 - Wiley Online Library
… efficiency of chemotherapy and overcome the MDR of cancer in a … of nanomaterials have
been rationally designed as carriers for … many nanovehicles have been developed to overcome

Nanomedicine to target multidrug resistant tumors

E Lepeltier, P Rijo, F Rizzolio, R Popovtzer… - Drug Resistance …, 2020 - Elsevier
nanovehicles capable of transporting and releasing the active therapeutic payload into target
cells, particularly in the case of cancer … strategy to combat cancer drug resistance: indeed, …

Tumor-permeated bioinspired theranostic nanovehicle remodels tumor immunosuppression for cancer therapy

H Wang, J Li, Z Wang, Y Wang, X Xu, X Gong, J Wang… - Biomaterials, 2021 - Elsevier
… gemcitabine in a ROS-sensitive manner to eliminate immunosuppressive cells. HPPH
was … Collectively, BTN was rationally designed with distinct legumain-specific reactivity, …

[HTML][HTML] Multifunctional nanoplatforms co-delivering combinatorial dual-drug for eliminating cancer multidrug resistance

X Wei, M Song, W Li, J Huang, G Yang, Y Wang - Theranostics, 2021 - ncbi.nlm.nih.gov
… of chemotherapy failure belongs to the occurrence of cancer … should not only be rationally
designed with multiple functions, … each drug release from nanovehicles is also worth exploring, …

Triple‐Combination Immunogenic Nanovesicles Reshape the Tumor Microenvironment to Potentiate Chemo‐Immunotherapy in Preclinical Cancer Models

X Shi, L Shu, M Wang, J Yao, Q Yao, S Bian… - Advanced …, 2023 - Wiley Online Library
nanovehicles. In this study, we generated a triple therapy-integrated nanoparticle (NP)
scaffold that overcomesChemotherapy-induced expression of immunosuppressive factors on …

[HTML][HTML] Rational design and latest advances of codelivery systems for cancer therapy

QY Meng, HL Cong, H Hu, FJ Xu - Materials Today Bio, 2020 - Elsevier
… typical design considerations about codelivery vectors for cancer … method of cancer treatments
include surgery, chemotherapy, … Yet chemotherapy still has some hurdles to overcome. (i) …

Nanotherapeutics approaches to overcome P-glycoprotein-mediated multi-drug resistance in cancer

J Halder, D Pradhan, B Kar, G Ghosh, G Rath - … , Biology and Medicine, 2022 - Elsevier
… importance of nanotechnology in cancer chemotherapy to combat P-gp … cancer, stating the
keen interest of the researchers to develop cancer nanomedicine to overcome drug resistance