[HTML][HTML] The relationship between reactive oxygen species and endothelial cell metabolism

R Alhayaza, E Haque, C Karbasiafshar… - Frontiers in …, 2020 - frontiersin.org
Vascular endothelial growth factor (VEGF) is the main driving … pathological conditions such
as tumor growth. According to the … In this type of angiogenesis, an endothelial tip cell secretes …

SIRT6 promotes angiogenesis and hemorrhage of carotid plaque via regulating HIF-1α and reactive oxygen species

Z Yang, Y Huang, L Zhu, K Yang, K Liang, J Tan… - Cell Death & …, 2021 - nature.com
… HIF-1α activates multiple genes contributing to the angiogenic process 21 . … vascular
endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF), which promote vascular

The multifaceted role of reactive oxygen species in tumorigenesis

A Kirtonia, G Sethi, M Garg - Cellular and Molecular Life Sciences, 2020 - Springer
… The depletion of NRF2 has displayed decreased tumor growth by enhancing oxidative stress-…
the migration of endothelial cells to tumor mass to promote angiogenesis through several …

Reactive oxygen species bridge the gap between chronic inflammation and tumor development

W Yu, Y Tu, Z Long, J Liu, D Kong… - Oxidative medicine …, 2022 - Wiley Online Library
… In this study, we assess the potential role of reactive oxygen species (ROS) … TAMs also
facilitate tumor-cell growth and angiogenesis by generating … Vascular endothelial growth factor …

Reactive Oxygen Species Induce Endothelial Differentiation of Liver Cancer Stem‐Like Sphere Cells through the Activation of Akt/IKK Signaling Pathway

Z Zhao, J Gao, C Li, X Xu, Y Hu… - Oxidative Medicine and …, 2020 - Wiley Online Library
… Because vascular endothelial cells are … angiogenic pattern, in which the endothelial cells
of HCC are derived from the transdifferentiation of CSCs and whether this process is regulated

A paradoxical role of reactive oxygen species in cancer signaling pathway: Physiology and pathology

V Ramalingam, R Rajaram - Process Biochemistry, 2021 - Elsevier
Vascular endothelial growth factor … of cancer cells by regulating angiogenesis, migration,
and invasion [42]. … mediate the tumor development by dysregulation of cell-cycle control and …

Reactive oxygen species (ROS): Critical roles in breast tumor microenvironment

RR Malla, N Surepalli, B Farran, SV Malhotra… - Critical Reviews in …, 2021 - Elsevier
… Increases in Reactive oxygen species (ROS) have been reported in … vascular endothelial
growth factor receptor … ROS also mediates angiogenesis dependent tumor growth in TME. …

[HTML][HTML] Dual role of reactive oxygen species and their application in cancer therapy

R Huang, H Chen, J Liang, Y Li, J Yang, C Luo… - … of Cancer, 2021 - ncbi.nlm.nih.gov
… inhibits tumor growth in two ways: (1) by blocking cancer cell … (2) by inducing cancer cell
death via activating endoplasmic … of vascular endothelial growth factor (VEGF) via stabilizing …

Reactive oxygen species (ROS): key components in cancer therapies

BM Sahoo, BK Banik, P Borah… - Anti-Cancer Agents in …, 2022 - ingentaconnect.com
tumor suppressor genes, and deoxyribonucleic acid repair genes via cellular intermediates
like reactive oxygen species … on the role of ROS in the various stages of cancer development. …

[HTML][HTML] Nox2 impairs VEGF-A-induced angiogenesis in placenta via mitochondrial ROS-STAT3 pathway

C Hu, Z Wu, Z Huang, X Hao, S Wang, J Deng, Y Yin… - Redox biology, 2021 - Elsevier
… deficiency facilitates angiogenesis in vitro and in vivo, and vascular endothelial … of reactive
oxygen species (ROS) in endothelial cells [12], and it also plays a vital role in angiogenesis. …