Remodeling of stromal cells and immune landscape in microenvironment during tumor progression
… focus on diversity of stromal cell population and immune inhabitants, whose subtypes create
the complexity of tumor microenvironment (TME), leading primary tumors … ) restoration leads …
the complexity of tumor microenvironment (TME), leading primary tumors … ) restoration leads …
Cancer: a mirrored room between tumor bulk and tumor microenvironment
P Hernández-Camarero, E López-Ruiz… - … & Clinical Cancer …, 2021 - Springer
… We also focus on the continuos feedback that is established … that stromal cells undergo due
to tumor corrupting activity. … between M2 macrophages and tissue repair/regeneration, it is …
to tumor corrupting activity. … between M2 macrophages and tissue repair/regeneration, it is …
Modifying the tumour microenvironment and reverting tumour cells: New strategies for treating malignant tumours
YQ Cheng, SB Wang, JH Liu, L Jin, Y Liu… - Cell …, 2020 - Wiley Online Library
… stromal cells, and CAFs are the main source of tumour cell … , and then rebuild the
haematopoietic microenvironment and … their tumour-promoting activity has become the focus of …
haematopoietic microenvironment and … their tumour-promoting activity has become the focus of …
Pancreatic cancer stroma: an update on therapeutic targeting strategies
… active cross-talk with cancer cells within the tumour microenvironment. The existence of
intratumoural … of these PDAC stroma components will be reviewed with an emphasis on potential …
intratumoural … of these PDAC stroma components will be reviewed with an emphasis on potential …
The tumor microenvironment
NM Anderson, MC Simon - Current Biology, 2020 - cell.com
… critical in wound healing and tissue repair. Monocyte-derived … tissue stroma to promote
critical steps in tumor formation, and … of cancer cells from the primary tumor microenvironment to …
critical steps in tumor formation, and … of cancer cells from the primary tumor microenvironment to …
[HTML][HTML] Radiotherapy-induced remodeling of the tumor microenvironment by stromal cells
TJ Berg, A Pietras - Seminars in cancer biology, 2022 - Elsevier
… tumor microenvironment are still being elucidated, we focus in this review on changes to
the … shown to surround brain metastases from multiple primary tumor types and promote an …
the … shown to surround brain metastases from multiple primary tumor types and promote an …
Stromal cells in the tumor microenvironment: accomplices of tumor progression?
Y Zhao, M Shen, L Wu, H Yang, Y Yao, Q Yang… - Cell Death & …, 2023 - nature.com
… for treatment of tumors based on stromal cells. We will focus on tumor-associated fibroblasts
… number of CAFs, reprogramming CAFs (restoring the phenotype of quiescent fibroblasts or …
… number of CAFs, reprogramming CAFs (restoring the phenotype of quiescent fibroblasts or …
The role of tumor microenvironment in cancer metastasis: Molecular mechanisms and therapeutic opportunities
… adjacent stromal cells begins at the earliest stages of tumor … normalization strategy involves
the restoration of a functional … tumors specifically by remodeling the TME, is focused on …
the restoration of a functional … tumors specifically by remodeling the TME, is focused on …
Role of MSC in the Tumor Microenvironment
R Hass - Cancers, 2020 - mdpi.com
… some important features of MSC within the tumor stroma. … to cancer cell-induced lesions to
promote tissue repair. … phosphorylation (OXPHOS), cancer cells focus on glycolysis, and the …
promote tissue repair. … phosphorylation (OXPHOS), cancer cells focus on glycolysis, and the …
Dynamic stromal alterations influence tumor-stroma crosstalk to promote pancreatic cancer and treatment resistance
KJ Murphy, CR Chambers, D Herrmann, P Timpson… - Cancers, 2021 - mdpi.com
… pancreatic tumor microenvironment (TME) can both promote and restrain PDAC development
and progression, with particular focus … Overall, the restoration of stromal homeostasis by …
and progression, with particular focus … Overall, the restoration of stromal homeostasis by …