[HTML][HTML] Current state and challenges in developing respiratory syncytial virus vaccines

C Biagi, A Dondi, S Scarpini, A Rocca, S Vandini… - Vaccines, 2020 - mdpi.com
… the state-of-the-art of the RSV vaccine research and its implications for clinical practice,
focusing on the characteristics of the vaccines that reached the clinical stage of development. …

[HTML][HTML] Multiepitope-based subunit vaccine design and evaluation against respiratory syncytial virus using reverse vaccinology approach

M Tahir ul Qamar, Z Shokat, I Muneer, UA Ashfaq… - Vaccines, 2020 - mdpi.com
… to develop a multiepitope-based subunit vaccine (MEV) using a reverse vaccinology approach
to curb RSV … associated with RSV vaccine development as, they can be used for maternal …

[HTML][HTML] The road to approved vaccines for respiratory syncytial virus

TJ Ruckwardt - NPJ vaccines, 2023 - nature.com
RSV on human health and how structure-based vaccine design set the stage for numerous
… For several decades, few live attenuated and purified fusion protein or subunit-based vaccine

[HTML][HTML] Intramuscular inoculation of AS02-adjuvanted respiratory syncytial virus (RSV) F subunit vaccine shows better efficiency and safety than subcutaneous …

L Bian, Y Zheng, X Guo, D Li, J Zhou, L Jing… - Frontiers in …, 2022 - frontiersin.org
… An effective RSV vaccine usually requires both high levels of RSV-neutralizing antibody
and Th1-like cellular immune response (36, 37). To explore the effect of immune routes on …

Subunit protein-based vaccines

V Apostolopoulos, VP Chavda - … Vaccination Technologies for Infectious …, 2024 - Elsevier
… Respiratory syncytial virus (RSV)-G glycoprotein subunit vaccine has been studied for its …
Here, we provided a snapshot of protein-subunit-based vaccines and their preclinical and …

CHO cells for virus-like particle and subunit vaccine manufacturing

ZV Sanchez-Martinez, SP Alpuche-Lazcano, M Stuible… - Vaccine, 2024 - Elsevier
… , including protein subunit-based (SUV) and … RSV vaccine also produced in genetically
engineered stable CHO cells by Pfizer, features a bivalent prefusion F formulation targeting RSV

Current situation and future perspectives of vaccines against respiratory syncytial virus

J Reina, EG de Herrero - Vacunas (English Edition), 2023 - Elsevier
… According to epidemiological data, there are three target populations that require different
approaches for the RSV vaccine: naive children < 4–6 months, children > 6 months, and >65 …

Nanoparticle vaccines against respiratory syncytial virus

LM Stephens, SM Varga - Future virology, 2020 - Taylor & Francis
… , nanoparticle-based, subunit-based, vector-… FI-RSV vaccine has led to prolonged concerns
about vaccine safety. Thus, one challenge in RSV vaccine development is that any vaccine

[HTML][HTML] … mRNA/lipid nanoparticle-based vaccines expressing respiratory syncytial virus F protein variants are immunogenic and protective in rodent models of RSV …

AS Espeseth, PJ Cejas, MP Citron, D Wang… - npj Vaccines, 2020 - nature.com
… by RSV in this population. However, the development of whole inactivated or subunit-based
vaccines for … elicited by a formalin-inactivated RSV vaccine candidate (FI-RSV). In contrast to …

[HTML][HTML] A single shot pre-fusion-stabilized bovine rsv f vaccine is safe and effective in newborn calves with maternally derived antibodies

S Riffault, S Hägglund, E Guzman, K Näslund… - Vaccines, 2020 - mdpi.com
… In the present study, we provide evidence that single-shot pre-F and N subunit-based
vaccines can protect calves vaccinated in the presence of BRSV-specific MDA. This can be …