Comparative Effectiveness of Implantable Defibrillators for Asymptomatic Brugada Syndrome: A Decision‐Analytic Model

S Khurshid, W Chen, WD Bode, JH Wasfy… - Journal of the …, 2021 - Am Heart Assoc
Brugada syndrome (BrS) is an inherited disorder associated with increased risk of sudden
cardiac death (SCD) attributable to ventricular arrhythmias. Yet SCD risk is variable and most …

Long-term prognosis of women with Brugada syndrome and electrophysiological study

…, A Baluja, O Campuzano, G Sarquella-Brugada… - Heart Rhythm, 2021 - Elsevier
Brugada syndrome (BrS) is an inherited disorder that presents with an electrocardiographic
(ECG) pattern of atypical right bundle branch block and ST-segment elevation in leads V 1 …

Deciphering the pathogenic role of a variant with uncertain significance for short QT and Brugada syndromes using gene‐edited human‐induced pluripotent stem cell …

I El‐Battrawy, H Lan, L Cyganek… - Clinical and …, 2021 - Wiley Online Library
… S480L is linked to the clinical phenotype of short QT syndrome 5 (SQTS5) overlapped with
Brugada syndrome (BrS). The PI3K pathway may contribute to the arrhythmogenesis of the …

Is Brugada Syndrome a Risk for Sudden Cardiac Death in Athletes? A Review of the Current Literature

…, N Jiang, IT Florica, JM Farina, J Brugada… - Current Treatment …, 2023 - Springer
… Literature supports low incidence of SCD in athletes with Brugada syndrome and limited …
treatment options and to augment safe participation in sport for athletes with Brugada syndrome

SCN5A compound heterozygosity mutation in Brugada syndrome: Functional consequences and the implication for pharmacological treatment

JV Joviano-Santos, A Santos-Miranda, EA Neri… - Life Sciences, 2021 - Elsevier
… SCN5A variants are the most common genetic alterations associated with Brugada
syndrome (BrS). In rare cases, compound heterozygosity is observed; however, its functional …

Recent Status in Brugada Syndrome.

F Bayrak, P Brugada - Archives of the Turkish Society of …, 2022 - search.ebscohost.com
Brugada syndrome was first described in 1992 as right … Brugada Syndrome is one of the
most common reasons for sudden … , and management of patients with Brugada Syndrome. …

Severity of Brugada syndrome disease manifestation and risk of new-onset depression or anxiety: a Danish nationwide study

CHB Jespersen, J Krøll, P Bhardwaj, BG Winkel… - Europace, 2023 - academic.oup.com
… We aimed to examine if a Brugada syndrome (BrS) diagnosis and symptomatic disease
presentation were associated with an increased risk of new-onset depression or anxiety and all-…

The role of clinical assessment and electrophysiology study in Brugada syndrome patients with syncope

…, A Iglesias, L Mont, R Brugada, J Brugada - American heart …, 2020 - Elsevier
… Cardiogenic syncope in Brugada syndrome (BrS) increases the risk of major events. …
This reflects a greater awareness in the Brugada syndrome diagnosis and the progressive …

Unravelling Novel SCN5A Mutations Linked to Brugada Syndrome: Functional, Structural, and Genetic Insights

A Frosio, E Micaglio, I Polsinelli, S Calamaio… - International Journal of …, 2023 - mdpi.com
… In conclusion, our data confirm that the clinical management of patients affected by Brugada
syndrome today requires a multidisciplinary approach. The genetic test is quite valuable, …

Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility

…, P Brugada, R Brugada, E Arbelo, J Brugada… - Nature …, 2022 - nature.com
Brugada syndrome (BrS) is a cardiac arrhythmia disorder associated with sudden death in
young adults. With the exception of SCN5A, encoding the cardiac sodium channel Na V 1.5, …