Can an implantable loop recorder improve risk stratification and appropriate management in Brugada syndrome?

F Gaita, N Cerrato, C Giustetto - European Heart Journal, 2024 - academic.oup.com
Brugada syndrome (BrS) is a genetic disorder with an increased risk of sudden death (SD)
in young people, in the absence of apparent structural heart disease. The diagnosis is …

Brugada syndrome as a major cause of sudden cardiac death in Asians

Y Nakano, W Shimizu - JACC: Asia, 2022 - jacc.org
… flow from diagnosis to treatment of Brugada Syndrome (BrS). BrS is diagnosed with a
spontaneously type 1 Brugada electrocardiogram (ECG) or type 1 Brugada ECG after provocative …

Treatment of Brugada Syndrome in 2023: Know Where You Come From to Know Where You Are Going

S Viskin, R Rosso - Circulation, 2023 - Am Heart Assoc
… for Brugada syndrome, but it consists of the largest series of patients who have undergone
epicardial ablation for symptomatic Brugada syndrome … of Brugada syndrome management. …

Brugada syndrome: from molecular mechanisms and genetics to risk stratification

IP Popa, DN Șerban, MA Mărănducă… - International Journal of …, 2023 - mdpi.com
… The predominance of cardiac transcription factor loci suggests that transcriptional regulation
is essential to the Brugada syndrome’s pathogenesis. It appears that BrS is a multifactorial …

Pathogenesis and management of Brugada syndrome in schizophrenia: A scoping review

A Rastogi, D Viani-Walsh, S Akbari, N Gall… - General Hospital …, 2020 - Elsevier
Brugada”, and “Brugada ECG patterns”. Nonetheless, emerging evidence of Brugada ECG
… Given that the existing literature on Brugada syndrome in schizophrenia is sparse, and non-…

Patient-specific iPSC-derived cardiomyocytes reveal variable phenotypic severity of Brugada syndrome

Y Sun, J Su, X Wang, J Wang, F Guo, H Qiu, H Fan… - …, 2023 - thelancet.com
Brugada syndrome (BrS) is a cardiac channelopathy that can result in sudden cardiac
death (SCD). SCN5A is the most frequent gene linked to BrS, but the genotype–phenotype …

Brugada syndrome: different experimental models and the role of human cardiomyocytes from induced pluripotent stem cells

Y Li, S Lang, I Akin, X Zhou… - Journal of the American …, 2022 - Am Heart Assoc
Brugada syndrome (BrS) is an inherited arrhythmic disorder that is characterized by an
increased risk of sudden cardiac death. It was first described in 1992 by research on 8 patients …

Role of catheter ablation for ventricular arrhythmias in Brugada syndrome

R Chokesuwattanaskul, K Nademanee - Current Cardiology Reports, 2021 - Springer
… Almost three decades ago when the clinical entity of Brugada syndrome (BrS) was described
in … the evidence-based guidelines for management and prevention of Brugada syndrome. …

A primary prevention clinical risk score model for patients with Brugada syndrome (BRUGADA-RISK)

…, Brugada Syndrome Risk Investigators - Clinical …, 2021 - jacc.org
… The goal of this study was to develop a risk score model for patients with Brugada syndrome
… cardiac death in patients with Brugada syndrome when comparing the presence and …

Gene therapy targeting protein trafficking regulator MOG1 in mouse models of Brugada syndrome, arrhythmias, and mild cardiomyopathy

G Yu, S Chakrabarti, M Tischenko, AL Chen… - Science Translational …, 2022 - science.org
… Mutations in SCN5A are associated with Brugada syndrome, an arrhythmic disorder that can
cause sudden cardiac death. Yu et al. generated a mouse model by knocking in an SCN5A …