[HTML][HTML] The role of epigenetic modifications for the pathogenesis of Crohn's disease

M Hornschuh, E Wirthgen, M Wolfien, KP Singh… - Clinical …, 2021 - Springer
recent years to which we refer the reader [13, 15,16,17]. In this review, we provide a deeper
insight into applied bioanalytical and computational tools for epigenetic analysis, as well as …

[HTML][HTML] Recent updates on the basic mechanisms and pathogenesis of inflammatory bowel diseases in experimental animal models

E Mizoguchi, D Low, Y Ezaki, T Okada - Intestinal research, 2020 - synapse.koreamed.org
pathogenesis of IBD and these models have been providing important insights into the
pathogenic … being explored for the development of small molecule treatment for IBD. For example, …

New and emerging treatments for inflammatory bowel disease

M Higashiyama, R Hokari - Digestion, 2023 - karger.com
reviewed not only the latest already or shortly available therapies but also emerging
Key Messages: Many kinds of new treatments are available, and promising treatments with …

[HTML][HTML] Ulcerative colitis: understanding its cellular pathology could provide insights into novel therapies

A Kaur, P Goggolidou - Journal of inflammation, 2020 - Springer
… Inflammatory Bowel Disease (IBD) is a term used to describe disorders that involve chronic
… colitis (UC) and Crohns disease (CD), another chronic inflammatory disease that causes …

IBD disease-modifying therapies: insights from emerging therapeutics

NG Kotla, Y Rochev - Trends in Molecular Medicine, 2023 - cell.com
… (s) and has emerged as one of the primary treatment targets in IBD. We review here current
… barrier dysregulation, conventional treatment goals, and the latest therapeutic strategies for …

[HTML][HTML] Dysbiosis in inflammatory bowel disease: pathogenic role and potential therapeutic targets

PT Santana, SLB Rosas, BE Ribeiro, Y Marinho… - … journal of molecular …, 2022 - mdpi.com
… factors have been suggested to mediate critical interactions between the exposome and
genome, offering new insights into the pathogenesis of several diseases, including IBD [147]. …

[HTML][HTML] New insights into the epigenetic regulation of inflammatory bowel disease

J Xu, H Xu, M Yang, Y Liang, Q Peng… - Frontiers in …, 2022 - frontiersin.org
new mechanisms of IBD. Our present review provided new insights into the pathophysiology
… Multi-omics integration analysis has emerged with the wide application of high-throughput …

[HTML][HTML] Metabolomics insights into inflammatory bowel disease: a comprehensive review

L Aldars-Garcia, JP Gisbert, M Chaparro - Pharmaceuticals, 2021 - mdpi.com
… be detected by metabolomic analysis and may provide insights into disease pathogenesis
[10]. The aim of the present review is to summarise the emerging contribution of metabolomics …

[HTML][HTML] miRNA-based potential biomarkers and new molecular insights in ulcerative colitis

…, J Liu, Y Gao, L Shen, S Li, S Chen - Frontiers in Pharmacology, 2021 - frontiersin.org
… In this review, we summarize the biosynthetic pathway and the function of miRNA, and …
These studies of miRNA have provided new insights into the molecular mechanism of UC. …

[HTML][HTML] Revisiting inflammatory bowel disease: pathology, treatments, challenges and emerging therapeutics including drug leads from natural products

K Yeshi, R Ruscher, L Hunter, NL Daly… - Journal of clinical …, 2020 - mdpi.com
insights into disease mechanism and identifying potential therapeutic targets. For example,
Gas Chromatography-Mass Spectrometry (GCMS)-based metabolomic profiling of dextran …