… h2 are essential histone methyltransferases for H3K9me3 on heterochromatin, and that
EHMT2 is a major H3K9me1 and H3K9me2 histone lysine methyltransferase of euchromatin and …

… histone methyltransferase G9a (KMT1C) and GLP or KMT1D are the members of family
Su(var)3-9, participate in mono- and di-methylation … The development of a potent inhibitor of G9a …

… (35) Moreover, discovery and development of G9a inhibitors has been a challenging task
in … (4 and 7 days) and western blotting analysis of histone methylation (7 and 12 days) in a …

… of G9a with many drugs is still under study. This article aims to summarize the role and
mechanism of G9a and its inhibitors in … progress in recent years to comprehensively understand …

… Despite recent progress in the development of non-nucleoside-… activity against G9a (EHMT2),
a histone methyltransferase … for the evaluation of in vivo efficacy of anticancer drugs. (43) …

… summarizes the recent progress in the development of histone methyltransferases (HMTs) …
SET-domain, along with the evaluation of the efficacy of G9a chemical inhibitors in various …

… In order to promote the development of a DNA methyltransferase inhibitor as an anti-tumor
agent, … As an inhibitor of histone methyltransferase G9a, studies have shown that CM-272 can …

… to target KMTs involved in histone methylation and epigenetic regulation, but these … with
classical chemotherapeutic agents and small molecule-targeted drugs, EZH2 and G9a can …

… This review discusses recent advances in cancer epigenetics … Anticancer drugs that alter
IDH and TET enzyme activity have … histone lysine methyltransferase 2 (G9A), the histone-lysine …

… G9a (EHMT2), a histone methyltransferase that catalyzes … Recent studies (12,13) have
shown that the responses of type I interferon impact to the efficacy of chemotherapeutic agents. …