… role of Drosophila PRRs in microbial recognition. We focus on the structure and function of
peptidoglycan recognition proteins (PGRPs) and Gram-negative bacteria-binding proteins (…

… We focus on the different domains and ligand recognition mechanisms between PRRs, …
promote the study of the role of the innate immune system in related diseases and even tumors. …

… immune system plays a pivotal role in the first line of host defense against infections and is
equipped with patterns recognition … microbial components and directly activate immune cells. …

… of pathogen-associated molecular patterns (PAMPs) that would otherwise activate an inducible
immune response through pattern recognition receptors (PRRs). In addition, many of the …

… activation of the innate immune system can aid a useful immune response to the vaccine, a
strong activation could lead to adverse effects ranging from febrile response to septic shock […

… A component of Gram-negative bacteria, extracellular LPS is sensed by our immune system
via the toll-like receptor (TLR)-4. Given that TLR4 is membrane bound, it recognizes LPS in …

… innate immune system activation related to cardiac damage. Sustained activation of the
innate immune system frequently results in maladaptive inflammatory responses that promote …

… immune cells and reduce intestinal permeability. An impaired interaction between gut bacteria
and the mucosal immune system … pathogenic gram-negative bacteria and their associated …

… patterns have shed new light on how microbes secrete OM vesicles (OMVs) … recognition
receptors on the membranes and in the cytosol of mammalian cells. We then detail how bacteria …

… While the importance of the innate immune system in responding to microorganisms is well
established, it is increasingly apparent that cytosolic receptors and their signaling pathways …