Oxidative stress in cardiovascular diseases

E Dubois-Deruy, V Peugnet, A Turkieh, F Pinet - Antioxidants, 2020 - mdpi.com
… in cardiovascular diseases progression. In this review, we will first detail the physiological
role of reactive oxygen species (… This process is called redox signaling and is defined as the …

Reactive oxygen species scavenging nanomedicine for the treatment of ischemic heart disease

Z Zhang, R Dalan, Z Hu, JW Wang… - Advanced …, 2022 - Wiley Online Library
… Enzymic sources of ROS are closely related to redox signaling in the vascular system. NOX,
XO, and … Patients with diabetes have a two to fourfold risk of cardiovascular diseases (CVDs) …

Reactive oxygen species in hypertension

LL Camargo, FJ Rios, AC Montezano… - Nature Reviews …, 2024 - nature.com
reactive oxygen species (ROS). ROS are small molecules derived from molecular oxygen
(O 2 ) and are generated by redox … or reduce cardiovascular events compared with placebo. …

[HTML][HTML] Redox-related biomarkers in human cardiovascular disease-classical footprints and beyond

A Daiber, O Hahad, I Andreadou, S Steven, S Daub… - Redox Biology, 2021 - Elsevier
cardiovascular diseases. This supports the concept that the formation of reactive oxygen and
nitrogen species … represents a hallmark of the leading cardiovascular comorbidities such as …

Reactive oxygen species and redox signaling in chronic kidney disease

MV Irazabal, VE Torres - Cells, 2020 - mdpi.com
… termination due to higher rate of cardiovascular events with Bardoxolone [96]. In this study,
Bardoxolone methyl did not reduce the risk of end stage kidney disease (ESRD) or death …

[HTML][HTML] Revisiting pharmacology of oxidative stress and endothelial dysfunction in cardiovascular disease: Evidence for redox-based therapies

A Daiber, S Chlopicki - Free Radical Biology and Medicine, 2020 - Elsevier
… adverse redox signalling … redox-based CVD therapies trying to explain why, despite a clear
link between endothelial dysfunction and adverse redox signalling and oxidative stress, redox

Thiol-based redox-active proteins as cardioprotective therapeutic agents in cardiovascular diseases

I Andreadou, P Efentakis, K Frenis, A Daiber… - Basic Research in …, 2021 - Springer
… thereby indirectly contribute to reactive oxygen species (ROS) … , which play an essential role
in the detoxification of hydrogen … redox signaling involved in various biological events in the …

Reactive sulfur species: a new redox player in cardiovascular pathophysiology

GK Kolluru, X Shen, CG Kevil - Arteriosclerosis, thrombosis, and …, 2020 - Am Heart Assoc
roles of RSS, associated oxidative stress redox signaling, and future research opportunities
in cardiovascular disease… H 2 S may subsequently react with reactive oxygen species (eg, …

The impact of reactive oxygen species in the development of cardiometabolic disorders: a review

R Akhigbe, A Ajayi - Lipids in Health and Disease, 2021 - Springer
Oxidative stress, an alteration in the balance between reactive oxygen species (ROS)
generation and antioxidant buffering capacity, has been implicated in the pathogenesis of …

The role of oxidative stress in cardiac disease: from physiological response to injury factor

R D'Oria, R Schipani, A Leonardini… - Oxidative medicine …, 2020 - Wiley Online Library
Reactive oxygen species (ROS) are highly reactive chemical … in cardiovascular diseases
related with oxidative stress. … coronary artery disease but has no effect on vascular redox state …